@article{93285c11fc164cdcb03d6664df8ef50a,
title = "Catalyst free, C-3 functionalization of imidazo[1,2-a]pyridines to rapidly access new chemical space for drug discovery efforts",
abstract = "Multicomponent reactions (MCRs) are robust tools for the rapid synthesis of complex, small molecule libraries for use in drug discovery and development. By utilizing MCR chemistry, we developed a protocol to functionalize the C-3 position of imidazo[1,2-a]pyridine through a three component, decarboxylation reaction involving imidazo[1,2-a]pyridine, glyoxalic acid, and boronic acid.",
author = "Naresh Gunaganti and Anupreet Kharbanda and Lakkaniga, {Naga Rajiv} and Lingtian Zhang and Rose Cooper and Li, {Hong yu} and Brendan Frett",
note = "Funding Information: This work was supported by an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health under grant number {\textquoteleft}{\textquoteleft}P20 GM109005{\textquoteright}{\textquoteright}. H. L. was supported by the grants NIH 1R01CA194094-010 and 1R01CA197178-01A1 and UAMS start-up funding. B. F. was supported by the UAMS Seeds of Science cancer research grant, the UAMS College of Pharmacy Seed Grant, and an ATA/Thyca research grant. Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",
year = "2018",
doi = "10.1039/C8CC07063F",
language = "English (US)",
volume = "54",
pages = "12954--12957",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "92",
}