Cavitary coccidioidomycosis with fungus ball formation: Diagnosis by fiberoptic bronchoscopy with coexistence of hyphae and spherules

R. E. Winn, R. Johnson, John N Galgiani, C. Butler, J. Pluss

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Pulmonary cavitary coccidioidomycosis with fungus ball formation was observed in two individuals with hemoptysis. The first patient had no overt compromise; the second was an insulin-dependent diabetic. In both, fiberoptic bronchoscopy was performed and cultures yielded Coccidioides immitis. The coexistence of spherules and hyphae of C immitis was seen histologically on bronchoscopic biopsy specimen of one cavitary lesion. Specific antifungal therapy and surgical excision were withheld and each patient has done well. This report provides for the first time nonsurgical confirmation that C immitis can produce an intracavitary fungus ball.

Original languageEnglish (US)
Pages (from-to)412-416
Number of pages5
JournalChest
Volume105
Issue number2
StatePublished - 1994
Externally publishedYes

Fingerprint

Coccidioidomycosis
Hyphae
Bronchoscopy
Fungi
Coccidioides
Hemoptysis
Insulin
Biopsy
Lung
Therapeutics

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Cavitary coccidioidomycosis with fungus ball formation : Diagnosis by fiberoptic bronchoscopy with coexistence of hyphae and spherules. / Winn, R. E.; Johnson, R.; Galgiani, John N; Butler, C.; Pluss, J.

In: Chest, Vol. 105, No. 2, 1994, p. 412-416.

Research output: Contribution to journalArticle

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