Cavitary coccidioidomycosis with fungus ball formation: Diagnosis by fiberoptic bronchoscopy with coexistence of hyphae and spherules

R. E. Winn, R. Johnson, J. N. Galgiani, C. Butler, J. Pluss

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Pulmonary cavitary coccidioidomycosis with fungus ball formation was observed in two individuals with hemoptysis. The first patient had no overt compromise; the second was an insulin-dependent diabetic. In both, fiberoptic bronchoscopy was performed and cultures yielded Coccidioides immitis. The coexistence of spherules and hyphae of C immitis was seen histologically on bronchoscopic biopsy specimen of one cavitary lesion. Specific antifungal therapy and surgical excision were withheld and each patient has done well. This report provides for the first time nonsurgical confirmation that C immitis can produce an intracavitary fungus ball.

Original languageEnglish (US)
Pages (from-to)412-416
Number of pages5
JournalCHEST
Volume105
Issue number2
DOIs
StatePublished - 1994

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Cavitary coccidioidomycosis with fungus ball formation: Diagnosis by fiberoptic bronchoscopy with coexistence of hyphae and spherules'. Together they form a unique fingerprint.

Cite this