Cell therapy for lung diseases report from an NIH-NHLBI workshop, november 13-14, 2012

Michael A. Matthay, Piero Anversa, Jahar Bhattacharya, Bruce K. Burnett, Harold A. Chapman, Joshua M. Hare, Derek J. Hei, Andrew M. Hoffman, Stella Kourembanas, David H. McKenna, Luis A. Ortiz, Harald C. Ott, William Tente, Bernard Thebaud, Bruce C. Trapnell, Daniel J. Weiss, Jason Yuan, Carol J. Blaisdell

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health convened the Cell Therapy for Lung Disease Working Group on November 13-14, 2012, to review and formulate recommendations for future research directions. The workshop brought together investigators studying basic mechanisms and the roles of cell therapy in preclinical models of lung injury and pulmonary vascular disease, with clinical trial experts in cell therapy for cardiovascular diseases and experts from the NHLBI Production Assistance for Cell Therapy program. The purpose of the workshop was to discuss the current status of basic investigations in lung cell therapy, to identify some of the scientific gaps in current knowledge regarding the potential roles and mechanismsof cell therapy in the treatment of lung diseases, and to develop recommendations to the NHLBI and the research community on scientific priorities and practical steps that would lead to first-in-human trials of lung cell therapy.

Original languageEnglish (US)
Pages (from-to)370-375
Number of pages6
JournalAmerican Journal of Respiratory and Critical Care Medicine
Volume188
Issue number3
DOIs
StatePublished - Aug 1 2013
Externally publishedYes

Fingerprint

National Heart, Lung, and Blood Institute (U.S.)
Cell- and Tissue-Based Therapy
Lung Diseases
Education
Lung
National Institutes of Health (U.S.)
Lung Injury
Vascular Diseases
Cardiovascular Diseases
Research Personnel
Clinical Trials
Research

Keywords

  • Epithelial and endothelial progenitor cells
  • Lung stem cells
  • Mesenchymal stromal (stem) cells

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine

Cite this

Matthay, M. A., Anversa, P., Bhattacharya, J., Burnett, B. K., Chapman, H. A., Hare, J. M., ... Blaisdell, C. J. (2013). Cell therapy for lung diseases report from an NIH-NHLBI workshop, november 13-14, 2012. American Journal of Respiratory and Critical Care Medicine, 188(3), 370-375. https://doi.org/10.1164/rccm.201303-0522WS

Cell therapy for lung diseases report from an NIH-NHLBI workshop, november 13-14, 2012. / Matthay, Michael A.; Anversa, Piero; Bhattacharya, Jahar; Burnett, Bruce K.; Chapman, Harold A.; Hare, Joshua M.; Hei, Derek J.; Hoffman, Andrew M.; Kourembanas, Stella; McKenna, David H.; Ortiz, Luis A.; Ott, Harald C.; Tente, William; Thebaud, Bernard; Trapnell, Bruce C.; Weiss, Daniel J.; Yuan, Jason; Blaisdell, Carol J.

In: American Journal of Respiratory and Critical Care Medicine, Vol. 188, No. 3, 01.08.2013, p. 370-375.

Research output: Contribution to journalArticle

Matthay, MA, Anversa, P, Bhattacharya, J, Burnett, BK, Chapman, HA, Hare, JM, Hei, DJ, Hoffman, AM, Kourembanas, S, McKenna, DH, Ortiz, LA, Ott, HC, Tente, W, Thebaud, B, Trapnell, BC, Weiss, DJ, Yuan, J & Blaisdell, CJ 2013, 'Cell therapy for lung diseases report from an NIH-NHLBI workshop, november 13-14, 2012', American Journal of Respiratory and Critical Care Medicine, vol. 188, no. 3, pp. 370-375. https://doi.org/10.1164/rccm.201303-0522WS
Matthay, Michael A. ; Anversa, Piero ; Bhattacharya, Jahar ; Burnett, Bruce K. ; Chapman, Harold A. ; Hare, Joshua M. ; Hei, Derek J. ; Hoffman, Andrew M. ; Kourembanas, Stella ; McKenna, David H. ; Ortiz, Luis A. ; Ott, Harald C. ; Tente, William ; Thebaud, Bernard ; Trapnell, Bruce C. ; Weiss, Daniel J. ; Yuan, Jason ; Blaisdell, Carol J. / Cell therapy for lung diseases report from an NIH-NHLBI workshop, november 13-14, 2012. In: American Journal of Respiratory and Critical Care Medicine. 2013 ; Vol. 188, No. 3. pp. 370-375.
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