Cellular studies of mammary tissue from cows hormonally induced into lactation: lactose and fatty acid synthesis.

Robert J Collier, W. J. Croom, D. E. Bauman, R. L. Hays, D. R. Nelson

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Temporal changes in ability of mammary gland to synthesize lactose and fatty acids were identified during the treatment of cows hormonally induced to lactate, and animal differences were compared to subsequent milk production. Hormonal treatment involved 17 beta-estradiol + progesterone on days 1 to 7 and dexamethasone on days 17 to 19. Mammary tissue obtained by biopsy on days 0, 8, 16, and 26 of treatment was examined for biosynthetic capacity by tissue slice incubations. In terms of peak daily milk yield, one cow was very successful (greater than 30 kg), two were intermediate (9 to 10 kg), and one cow was unsuccessful (less than 3 kg). Differences between cows in the capability to synthesize lactose and fatty acids were evident as early as day 8 and were further magnified by day 16. In particular, the tissue from the successful cow was undergoing lactogenesis by day 8 while this was not evident until the day 16 biopsy sample in the less successful cows. In contrast to the other cows, tissues from the unsuccessful animal regressed in its ability to synthesize lactose and fatty acids between day 16 and 26. Relative differences between animals in measurements of metabolic capacity were consistent with subsequent milk production.

Original languageEnglish (US)
Pages (from-to)1226-1231
Number of pages6
JournalJournal of Dairy Science
Volume59
Issue number7
StatePublished - Jul 1976
Externally publishedYes

Fingerprint

Lactose
Lactation
lactose
breasts
Breast
Fatty Acids
lactation
fatty acids
cows
Milk
synthesis
Biopsy
Human Mammary Glands
biopsy
milk production
Dexamethasone
Progesterone
Estradiol
Lactic Acid
milk synthesis

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Food Science
  • veterinary(all)

Cite this

Cellular studies of mammary tissue from cows hormonally induced into lactation : lactose and fatty acid synthesis. / Collier, Robert J; Croom, W. J.; Bauman, D. E.; Hays, R. L.; Nelson, D. R.

In: Journal of Dairy Science, Vol. 59, No. 7, 07.1976, p. 1226-1231.

Research output: Contribution to journalArticle

Collier, Robert J ; Croom, W. J. ; Bauman, D. E. ; Hays, R. L. ; Nelson, D. R. / Cellular studies of mammary tissue from cows hormonally induced into lactation : lactose and fatty acid synthesis. In: Journal of Dairy Science. 1976 ; Vol. 59, No. 7. pp. 1226-1231.
@article{885fb06a1a704414ad21d9acd8af47e3,
title = "Cellular studies of mammary tissue from cows hormonally induced into lactation: lactose and fatty acid synthesis.",
abstract = "Temporal changes in ability of mammary gland to synthesize lactose and fatty acids were identified during the treatment of cows hormonally induced to lactate, and animal differences were compared to subsequent milk production. Hormonal treatment involved 17 beta-estradiol + progesterone on days 1 to 7 and dexamethasone on days 17 to 19. Mammary tissue obtained by biopsy on days 0, 8, 16, and 26 of treatment was examined for biosynthetic capacity by tissue slice incubations. In terms of peak daily milk yield, one cow was very successful (greater than 30 kg), two were intermediate (9 to 10 kg), and one cow was unsuccessful (less than 3 kg). Differences between cows in the capability to synthesize lactose and fatty acids were evident as early as day 8 and were further magnified by day 16. In particular, the tissue from the successful cow was undergoing lactogenesis by day 8 while this was not evident until the day 16 biopsy sample in the less successful cows. In contrast to the other cows, tissues from the unsuccessful animal regressed in its ability to synthesize lactose and fatty acids between day 16 and 26. Relative differences between animals in measurements of metabolic capacity were consistent with subsequent milk production.",
author = "Collier, {Robert J} and Croom, {W. J.} and Bauman, {D. E.} and Hays, {R. L.} and Nelson, {D. R.}",
year = "1976",
month = "7",
language = "English (US)",
volume = "59",
pages = "1226--1231",
journal = "Journal of Dairy Science",
issn = "0022-0302",
publisher = "Elsevier Limited",
number = "7",

}

TY - JOUR

T1 - Cellular studies of mammary tissue from cows hormonally induced into lactation

T2 - lactose and fatty acid synthesis.

AU - Collier, Robert J

AU - Croom, W. J.

AU - Bauman, D. E.

AU - Hays, R. L.

AU - Nelson, D. R.

PY - 1976/7

Y1 - 1976/7

N2 - Temporal changes in ability of mammary gland to synthesize lactose and fatty acids were identified during the treatment of cows hormonally induced to lactate, and animal differences were compared to subsequent milk production. Hormonal treatment involved 17 beta-estradiol + progesterone on days 1 to 7 and dexamethasone on days 17 to 19. Mammary tissue obtained by biopsy on days 0, 8, 16, and 26 of treatment was examined for biosynthetic capacity by tissue slice incubations. In terms of peak daily milk yield, one cow was very successful (greater than 30 kg), two were intermediate (9 to 10 kg), and one cow was unsuccessful (less than 3 kg). Differences between cows in the capability to synthesize lactose and fatty acids were evident as early as day 8 and were further magnified by day 16. In particular, the tissue from the successful cow was undergoing lactogenesis by day 8 while this was not evident until the day 16 biopsy sample in the less successful cows. In contrast to the other cows, tissues from the unsuccessful animal regressed in its ability to synthesize lactose and fatty acids between day 16 and 26. Relative differences between animals in measurements of metabolic capacity were consistent with subsequent milk production.

AB - Temporal changes in ability of mammary gland to synthesize lactose and fatty acids were identified during the treatment of cows hormonally induced to lactate, and animal differences were compared to subsequent milk production. Hormonal treatment involved 17 beta-estradiol + progesterone on days 1 to 7 and dexamethasone on days 17 to 19. Mammary tissue obtained by biopsy on days 0, 8, 16, and 26 of treatment was examined for biosynthetic capacity by tissue slice incubations. In terms of peak daily milk yield, one cow was very successful (greater than 30 kg), two were intermediate (9 to 10 kg), and one cow was unsuccessful (less than 3 kg). Differences between cows in the capability to synthesize lactose and fatty acids were evident as early as day 8 and were further magnified by day 16. In particular, the tissue from the successful cow was undergoing lactogenesis by day 8 while this was not evident until the day 16 biopsy sample in the less successful cows. In contrast to the other cows, tissues from the unsuccessful animal regressed in its ability to synthesize lactose and fatty acids between day 16 and 26. Relative differences between animals in measurements of metabolic capacity were consistent with subsequent milk production.

UR - http://www.scopus.com/inward/record.url?scp=0016979294&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016979294&partnerID=8YFLogxK

M3 - Article

C2 - 985832

AN - SCOPUS:0016979294

VL - 59

SP - 1226

EP - 1231

JO - Journal of Dairy Science

JF - Journal of Dairy Science

SN - 0022-0302

IS - 7

ER -