Cellular trafficking of nicotinic acetylcholine receptors

Research output: Contribution to journalReview article

20 Scopus citations

Abstract

Nicotinic acetylcholine receptors (nAChRs) play critical roles throughout the body. Precise regulation of the cellular location and availability of nAChRs on neurons and target cells is critical to their proper function. Dynamic, post-translational regulation of nAChRs, particularly control of their movements among the different compartments of cells, is an important aspect of that regulation. A combination of new information and new techniques has the study of nAChR trafficking poised for new breakthroughs.

Original languageEnglish (US)
Pages (from-to)656-662
Number of pages7
JournalActa Pharmacologica Sinica
Volume30
Issue number6
DOIs
StatePublished - Jun 1 2009

Keywords

  • Biosynthesis
  • Endocytosis
  • Endoplasmic reticulum-associated degradation
  • Membrane traffic
  • Protein traffic

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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