Chalcogenide glass sensors for bio-molecule detection

Pierre Lucas, Garrett J. Coleman, Christopher Cantoni, Shibin Jiang, Tao Luo, Bruno Bureau, Catherine Boussard-Pledel, Johann Troles, Zhiyong Yang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Citations (Scopus)

Abstract

Chalcogenide glasses constitute the only class of materials that remain fully amorphous while exhibiting broad optical transparency over the full infrared region from 2-20 microns. As such, they can be shaped into complex optical elements while retaining a clear optical window that encompass the vibrational signals of virtually any molecules. Chalcogenide glasses are therefore ideal materials for designing biological and chemical sensors based on vibrational spectroscopy. In this paper we review the properties of these glasses and the corresponding design of optical elements for bio-chemical sensing. Amorphous chalcogenides offer a very wide compositional landscape that permit to tune their physical properties to match specific demands for the production of optical devices. This includes tailoring the infrared window over specific ranges of wavelength such as the long-wave infrared region to capture important vibrational signal including the "signature region" of micro-organisms or the bending mode of CO2 molecules. Additionally, compositional engineering enables tuning the viscosity-temperature dependence of the glass melt in order to control the rheological properties that are fundamental to the production of glass elements. Indeed, exquisite control of the viscosity is key to the fabrication process of many optical elements such as fiber drawing, lens molding, surface embossing or reflow of microresonators. Optimal control of these properties then enables the design and fabrication of optimized infrared sensors such as Fiber Evanescent Wave Spectroscopy (FEWS) sensors, Whispering Gallery Modes (WGM) micro-resonator sensors, nanostructured surfaces for integrated optics and surface-enhanced processes, or lens molding for focused collection of infrared signals. Many of these sensor designs can be adapted to collect and monitor the vibrational signal of live microorganisms to study their metabolism in controlled environmental conditions. Further materials engineering enable the design of opto-electrophoretic sensors that permit simultaneous capture and detection of hazardous bio-molecules such as bacteria, virus and proteins using a conducting glass that serves as both an electrode and an optical elements. Upon adequate spectral analysis such as Principal Component Analysis (PCA) or Partial Least Square (PLS) regression these devices enable highly selective identification of hazardous microorganism such as different strains of bacteria and food pathogens.

Original languageEnglish (US)
Title of host publicationOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII
PublisherSPIE
Volume10058
ISBN (Electronic)9781510605572
DOIs
StatePublished - 2017
EventOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII - San Francisco, United States
Duration: Jan 28 2017Jan 29 2017

Other

OtherOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII
CountryUnited States
CitySan Francisco
Period1/28/171/29/17

Fingerprint

Glass
Optical devices
Molecules
glass
Infrared radiation
sensors
Sensors
molecules
microorganisms
Viscosity
Molding
Microorganisms
bacteria
Lenses
Optical Phenomena
Spectrum Analysis
Bacteria
lenses
engineering
infrared windows

Keywords

  • Bio-sensors
  • Chalcogenide glass
  • Infrared fibers
  • Infrared materials
  • Infrared spectroscopy
  • Microresonators. Evanescent wave spectroscopy
  • Vibrational spectroscopy

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Lucas, P., Coleman, G. J., Cantoni, C., Jiang, S., Luo, T., Bureau, B., ... Yang, Z. (2017). Chalcogenide glass sensors for bio-molecule detection. In Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII (Vol. 10058). [100580Q] SPIE. https://doi.org/10.1117/12.2257995

Chalcogenide glass sensors for bio-molecule detection. / Lucas, Pierre; Coleman, Garrett J.; Cantoni, Christopher; Jiang, Shibin; Luo, Tao; Bureau, Bruno; Boussard-Pledel, Catherine; Troles, Johann; Yang, Zhiyong.

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII. Vol. 10058 SPIE, 2017. 100580Q.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lucas, P, Coleman, GJ, Cantoni, C, Jiang, S, Luo, T, Bureau, B, Boussard-Pledel, C, Troles, J & Yang, Z 2017, Chalcogenide glass sensors for bio-molecule detection. in Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII. vol. 10058, 100580Q, SPIE, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII, San Francisco, United States, 1/28/17. https://doi.org/10.1117/12.2257995
Lucas P, Coleman GJ, Cantoni C, Jiang S, Luo T, Bureau B et al. Chalcogenide glass sensors for bio-molecule detection. In Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII. Vol. 10058. SPIE. 2017. 100580Q https://doi.org/10.1117/12.2257995
Lucas, Pierre ; Coleman, Garrett J. ; Cantoni, Christopher ; Jiang, Shibin ; Luo, Tao ; Bureau, Bruno ; Boussard-Pledel, Catherine ; Troles, Johann ; Yang, Zhiyong. / Chalcogenide glass sensors for bio-molecule detection. Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII. Vol. 10058 SPIE, 2017.
@inproceedings{1b83f2961b7b4b7997976ac67ed4c1da,
title = "Chalcogenide glass sensors for bio-molecule detection",
abstract = "Chalcogenide glasses constitute the only class of materials that remain fully amorphous while exhibiting broad optical transparency over the full infrared region from 2-20 microns. As such, they can be shaped into complex optical elements while retaining a clear optical window that encompass the vibrational signals of virtually any molecules. Chalcogenide glasses are therefore ideal materials for designing biological and chemical sensors based on vibrational spectroscopy. In this paper we review the properties of these glasses and the corresponding design of optical elements for bio-chemical sensing. Amorphous chalcogenides offer a very wide compositional landscape that permit to tune their physical properties to match specific demands for the production of optical devices. This includes tailoring the infrared window over specific ranges of wavelength such as the long-wave infrared region to capture important vibrational signal including the {"}signature region{"} of micro-organisms or the bending mode of CO2 molecules. Additionally, compositional engineering enables tuning the viscosity-temperature dependence of the glass melt in order to control the rheological properties that are fundamental to the production of glass elements. Indeed, exquisite control of the viscosity is key to the fabrication process of many optical elements such as fiber drawing, lens molding, surface embossing or reflow of microresonators. Optimal control of these properties then enables the design and fabrication of optimized infrared sensors such as Fiber Evanescent Wave Spectroscopy (FEWS) sensors, Whispering Gallery Modes (WGM) micro-resonator sensors, nanostructured surfaces for integrated optics and surface-enhanced processes, or lens molding for focused collection of infrared signals. Many of these sensor designs can be adapted to collect and monitor the vibrational signal of live microorganisms to study their metabolism in controlled environmental conditions. Further materials engineering enable the design of opto-electrophoretic sensors that permit simultaneous capture and detection of hazardous bio-molecules such as bacteria, virus and proteins using a conducting glass that serves as both an electrode and an optical elements. Upon adequate spectral analysis such as Principal Component Analysis (PCA) or Partial Least Square (PLS) regression these devices enable highly selective identification of hazardous microorganism such as different strains of bacteria and food pathogens.",
keywords = "Bio-sensors, Chalcogenide glass, Infrared fibers, Infrared materials, Infrared spectroscopy, Microresonators. Evanescent wave spectroscopy, Vibrational spectroscopy",
author = "Pierre Lucas and Coleman, {Garrett J.} and Christopher Cantoni and Shibin Jiang and Tao Luo and Bruno Bureau and Catherine Boussard-Pledel and Johann Troles and Zhiyong Yang",
year = "2017",
doi = "10.1117/12.2257995",
language = "English (US)",
volume = "10058",
booktitle = "Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII",
publisher = "SPIE",
address = "United States",

}

TY - GEN

T1 - Chalcogenide glass sensors for bio-molecule detection

AU - Lucas, Pierre

AU - Coleman, Garrett J.

AU - Cantoni, Christopher

AU - Jiang, Shibin

AU - Luo, Tao

AU - Bureau, Bruno

AU - Boussard-Pledel, Catherine

AU - Troles, Johann

AU - Yang, Zhiyong

PY - 2017

Y1 - 2017

N2 - Chalcogenide glasses constitute the only class of materials that remain fully amorphous while exhibiting broad optical transparency over the full infrared region from 2-20 microns. As such, they can be shaped into complex optical elements while retaining a clear optical window that encompass the vibrational signals of virtually any molecules. Chalcogenide glasses are therefore ideal materials for designing biological and chemical sensors based on vibrational spectroscopy. In this paper we review the properties of these glasses and the corresponding design of optical elements for bio-chemical sensing. Amorphous chalcogenides offer a very wide compositional landscape that permit to tune their physical properties to match specific demands for the production of optical devices. This includes tailoring the infrared window over specific ranges of wavelength such as the long-wave infrared region to capture important vibrational signal including the "signature region" of micro-organisms or the bending mode of CO2 molecules. Additionally, compositional engineering enables tuning the viscosity-temperature dependence of the glass melt in order to control the rheological properties that are fundamental to the production of glass elements. Indeed, exquisite control of the viscosity is key to the fabrication process of many optical elements such as fiber drawing, lens molding, surface embossing or reflow of microresonators. Optimal control of these properties then enables the design and fabrication of optimized infrared sensors such as Fiber Evanescent Wave Spectroscopy (FEWS) sensors, Whispering Gallery Modes (WGM) micro-resonator sensors, nanostructured surfaces for integrated optics and surface-enhanced processes, or lens molding for focused collection of infrared signals. Many of these sensor designs can be adapted to collect and monitor the vibrational signal of live microorganisms to study their metabolism in controlled environmental conditions. Further materials engineering enable the design of opto-electrophoretic sensors that permit simultaneous capture and detection of hazardous bio-molecules such as bacteria, virus and proteins using a conducting glass that serves as both an electrode and an optical elements. Upon adequate spectral analysis such as Principal Component Analysis (PCA) or Partial Least Square (PLS) regression these devices enable highly selective identification of hazardous microorganism such as different strains of bacteria and food pathogens.

AB - Chalcogenide glasses constitute the only class of materials that remain fully amorphous while exhibiting broad optical transparency over the full infrared region from 2-20 microns. As such, they can be shaped into complex optical elements while retaining a clear optical window that encompass the vibrational signals of virtually any molecules. Chalcogenide glasses are therefore ideal materials for designing biological and chemical sensors based on vibrational spectroscopy. In this paper we review the properties of these glasses and the corresponding design of optical elements for bio-chemical sensing. Amorphous chalcogenides offer a very wide compositional landscape that permit to tune their physical properties to match specific demands for the production of optical devices. This includes tailoring the infrared window over specific ranges of wavelength such as the long-wave infrared region to capture important vibrational signal including the "signature region" of micro-organisms or the bending mode of CO2 molecules. Additionally, compositional engineering enables tuning the viscosity-temperature dependence of the glass melt in order to control the rheological properties that are fundamental to the production of glass elements. Indeed, exquisite control of the viscosity is key to the fabrication process of many optical elements such as fiber drawing, lens molding, surface embossing or reflow of microresonators. Optimal control of these properties then enables the design and fabrication of optimized infrared sensors such as Fiber Evanescent Wave Spectroscopy (FEWS) sensors, Whispering Gallery Modes (WGM) micro-resonator sensors, nanostructured surfaces for integrated optics and surface-enhanced processes, or lens molding for focused collection of infrared signals. Many of these sensor designs can be adapted to collect and monitor the vibrational signal of live microorganisms to study their metabolism in controlled environmental conditions. Further materials engineering enable the design of opto-electrophoretic sensors that permit simultaneous capture and detection of hazardous bio-molecules such as bacteria, virus and proteins using a conducting glass that serves as both an electrode and an optical elements. Upon adequate spectral analysis such as Principal Component Analysis (PCA) or Partial Least Square (PLS) regression these devices enable highly selective identification of hazardous microorganism such as different strains of bacteria and food pathogens.

KW - Bio-sensors

KW - Chalcogenide glass

KW - Infrared fibers

KW - Infrared materials

KW - Infrared spectroscopy

KW - Microresonators. Evanescent wave spectroscopy

KW - Vibrational spectroscopy

UR - http://www.scopus.com/inward/record.url?scp=85018919448&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85018919448&partnerID=8YFLogxK

U2 - 10.1117/12.2257995

DO - 10.1117/12.2257995

M3 - Conference contribution

AN - SCOPUS:85018919448

VL - 10058

BT - Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII

PB - SPIE

ER -