We have developed a miniaturized ultrasound device that attaches to the gastrointestinal mucosa by suction and produces high-resolution (±0.1 mm) images of the layers of the intestinal wall. The esophageal wall layers in a single sheep were measured during 20 occlusive contractions observed with simultaneous endoscopy, which revealed thickening of the inner circular muscle layer from 1.2 ± 0.2 mm to 2.2 ± 0.4 mm (p < 0.01), and during 20 dilations demonstrating thinning of the full thickness of the esophageal wall from 3.6 ± 0.3 mm to 2.9 ± 0.3 mm (p < 0.01). Safety experiments performed in two canine stomachs demonstrated no erosions or ulceration at any level of suction. Our investigations indicate that the M-mode suction ultrasound device can safely assess changes occurring in the layers of the esophageal wall during contractions and dilations and should be evaluated for the study of human intestinal motility. (Gastrointest Endosc 1993;33: 146-52.).
|Original language||English (US)|
|Title of host publication||Basic And New Aspects Of Gastrointestinal Ultrasonography|
|Publisher||World Scientific Publishing Co.|
|Number of pages||7|
|State||Published - Jan 1 2005|
ASJC Scopus subject areas