Chapter 1.4 Episodic memory: reconsolidation

Lynn Nadel, Almut Hupbach, Oliver Hardt, Rebecca L Gomez

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

In contrast to the accepted wisdom that memories become fixed over time, recent evidence has renewed interest in the dynamic quality of memory, suggesting that even old memories are subject to revision and reconsolidation given the right circumstances. We discuss a new paradigm developed to study reconsolidation of episodic memory in humans, showing that reminders can open a previously established memory to updating based on new experience. We show that under laboratory conditions the experimental context plays a critical role in determining whether or not such memory updating will occur; but that under conditions where the context is highly familiar other factors might play this role. The nature of context is explored, linking our results to work on hippocampus, and the results of a neuroimaging study exploring the impact of reactivation of well-established memory are described. Our results, situated within a broader context, set the stage for future explorations of the cognitive neuroscience of the malleability of memory.

Original languageEnglish (US)
Pages (from-to)43-56
Number of pages14
JournalHandbook of Behavioral Neuroscience
Volume18
DOIs
StatePublished - 2008

Fingerprint

Episodic Memory
Neuroimaging
Hippocampus

Keywords

  • context
  • episodic memory
  • hippocampus
  • reconsolidation

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Cognitive Neuroscience

Cite this

Chapter 1.4 Episodic memory : reconsolidation. / Nadel, Lynn; Hupbach, Almut; Hardt, Oliver; Gomez, Rebecca L.

In: Handbook of Behavioral Neuroscience, Vol. 18, 2008, p. 43-56.

Research output: Contribution to journalArticle

@article{e31e0c28233743aea9af70953f96c454,
title = "Chapter 1.4 Episodic memory: reconsolidation",
abstract = "In contrast to the accepted wisdom that memories become fixed over time, recent evidence has renewed interest in the dynamic quality of memory, suggesting that even old memories are subject to revision and reconsolidation given the right circumstances. We discuss a new paradigm developed to study reconsolidation of episodic memory in humans, showing that reminders can open a previously established memory to updating based on new experience. We show that under laboratory conditions the experimental context plays a critical role in determining whether or not such memory updating will occur; but that under conditions where the context is highly familiar other factors might play this role. The nature of context is explored, linking our results to work on hippocampus, and the results of a neuroimaging study exploring the impact of reactivation of well-established memory are described. Our results, situated within a broader context, set the stage for future explorations of the cognitive neuroscience of the malleability of memory.",
keywords = "context, episodic memory, hippocampus, reconsolidation",
author = "Lynn Nadel and Almut Hupbach and Oliver Hardt and Gomez, {Rebecca L}",
year = "2008",
doi = "10.1016/S1569-7339(08)00204-X",
language = "English (US)",
volume = "18",
pages = "43--56",
journal = "Handbook of Behavioral Neuroscience",
issn = "1569-7339",
publisher = "Elsevier",

}

TY - JOUR

T1 - Chapter 1.4 Episodic memory

T2 - reconsolidation

AU - Nadel, Lynn

AU - Hupbach, Almut

AU - Hardt, Oliver

AU - Gomez, Rebecca L

PY - 2008

Y1 - 2008

N2 - In contrast to the accepted wisdom that memories become fixed over time, recent evidence has renewed interest in the dynamic quality of memory, suggesting that even old memories are subject to revision and reconsolidation given the right circumstances. We discuss a new paradigm developed to study reconsolidation of episodic memory in humans, showing that reminders can open a previously established memory to updating based on new experience. We show that under laboratory conditions the experimental context plays a critical role in determining whether or not such memory updating will occur; but that under conditions where the context is highly familiar other factors might play this role. The nature of context is explored, linking our results to work on hippocampus, and the results of a neuroimaging study exploring the impact of reactivation of well-established memory are described. Our results, situated within a broader context, set the stage for future explorations of the cognitive neuroscience of the malleability of memory.

AB - In contrast to the accepted wisdom that memories become fixed over time, recent evidence has renewed interest in the dynamic quality of memory, suggesting that even old memories are subject to revision and reconsolidation given the right circumstances. We discuss a new paradigm developed to study reconsolidation of episodic memory in humans, showing that reminders can open a previously established memory to updating based on new experience. We show that under laboratory conditions the experimental context plays a critical role in determining whether or not such memory updating will occur; but that under conditions where the context is highly familiar other factors might play this role. The nature of context is explored, linking our results to work on hippocampus, and the results of a neuroimaging study exploring the impact of reactivation of well-established memory are described. Our results, situated within a broader context, set the stage for future explorations of the cognitive neuroscience of the malleability of memory.

KW - context

KW - episodic memory

KW - hippocampus

KW - reconsolidation

UR - http://www.scopus.com/inward/record.url?scp=67649739114&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67649739114&partnerID=8YFLogxK

U2 - 10.1016/S1569-7339(08)00204-X

DO - 10.1016/S1569-7339(08)00204-X

M3 - Article

AN - SCOPUS:67649739114

VL - 18

SP - 43

EP - 56

JO - Handbook of Behavioral Neuroscience

JF - Handbook of Behavioral Neuroscience

SN - 1569-7339

ER -