Characterization of hepatitis C infection in tuberculosis patients in an urban city in the USA

M. Campo, A. Shrestha, Eyal - Oren, H. Thiede, J. Duchin, M. Narita, K. Crothers

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The impact of hepatitis C virus infection (HCI), the most common bloodborne virus infection in the USA, on outcome of active tuberculosis (TB) treatment is largely unknown. We aimed to describe characteristics of TB patients with hepatitis C virus infection (TB-HCI) in King County, Washington, including TB treatment duration and outcome. We reviewed 1510 records of patients treated for active TB at the Public Health - Seattle & King County Tuberculosis Control Program between 2000 and 2010, and identified 53 with HCI. Advanced age, being born in the USA, HIV infection, homelessness and injection drug use were independently associated with HCI in TB cases. Independent factors associated with increased treatment duration included HIV infection, excess alcohol use, extrapulmonary TB, and any drug-resistant TB disease. Our findings suggest that TB-HCI patients can be successfully treated for active TB without extending treatment duration.

Original languageEnglish (US)
Pages (from-to)1459-1466
Number of pages8
JournalEpidemiology and Infection
Volume142
Issue number7
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

Hepatitis C
Tuberculosis
Virus Diseases
Hepacivirus
Infection
HIV Infections
Homeless Persons
Multidrug-Resistant Tuberculosis
Therapeutics
Public Health
Alcohols
Injections

Keywords

  • Hepatitis C
  • tuberculosis (TB)

ASJC Scopus subject areas

  • Infectious Diseases
  • Epidemiology

Cite this

Characterization of hepatitis C infection in tuberculosis patients in an urban city in the USA. / Campo, M.; Shrestha, A.; Oren, Eyal -; Thiede, H.; Duchin, J.; Narita, M.; Crothers, K.

In: Epidemiology and Infection, Vol. 142, No. 7, 2014, p. 1459-1466.

Research output: Contribution to journalArticle

Campo, M. ; Shrestha, A. ; Oren, Eyal - ; Thiede, H. ; Duchin, J. ; Narita, M. ; Crothers, K. / Characterization of hepatitis C infection in tuberculosis patients in an urban city in the USA. In: Epidemiology and Infection. 2014 ; Vol. 142, No. 7. pp. 1459-1466.
@article{02fc4897bdf34ecc83c0f9a1cfcd4881,
title = "Characterization of hepatitis C infection in tuberculosis patients in an urban city in the USA",
abstract = "The impact of hepatitis C virus infection (HCI), the most common bloodborne virus infection in the USA, on outcome of active tuberculosis (TB) treatment is largely unknown. We aimed to describe characteristics of TB patients with hepatitis C virus infection (TB-HCI) in King County, Washington, including TB treatment duration and outcome. We reviewed 1510 records of patients treated for active TB at the Public Health - Seattle & King County Tuberculosis Control Program between 2000 and 2010, and identified 53 with HCI. Advanced age, being born in the USA, HIV infection, homelessness and injection drug use were independently associated with HCI in TB cases. Independent factors associated with increased treatment duration included HIV infection, excess alcohol use, extrapulmonary TB, and any drug-resistant TB disease. Our findings suggest that TB-HCI patients can be successfully treated for active TB without extending treatment duration.",
keywords = "Hepatitis C, tuberculosis (TB)",
author = "M. Campo and A. Shrestha and Oren, {Eyal -} and H. Thiede and J. Duchin and M. Narita and K. Crothers",
year = "2014",
doi = "10.1017/S0950268813002355",
language = "English (US)",
volume = "142",
pages = "1459--1466",
journal = "Epidemiology and Infection",
issn = "0950-2688",
publisher = "Cambridge University Press",
number = "7",

}

TY - JOUR

T1 - Characterization of hepatitis C infection in tuberculosis patients in an urban city in the USA

AU - Campo, M.

AU - Shrestha, A.

AU - Oren, Eyal -

AU - Thiede, H.

AU - Duchin, J.

AU - Narita, M.

AU - Crothers, K.

PY - 2014

Y1 - 2014

N2 - The impact of hepatitis C virus infection (HCI), the most common bloodborne virus infection in the USA, on outcome of active tuberculosis (TB) treatment is largely unknown. We aimed to describe characteristics of TB patients with hepatitis C virus infection (TB-HCI) in King County, Washington, including TB treatment duration and outcome. We reviewed 1510 records of patients treated for active TB at the Public Health - Seattle & King County Tuberculosis Control Program between 2000 and 2010, and identified 53 with HCI. Advanced age, being born in the USA, HIV infection, homelessness and injection drug use were independently associated with HCI in TB cases. Independent factors associated with increased treatment duration included HIV infection, excess alcohol use, extrapulmonary TB, and any drug-resistant TB disease. Our findings suggest that TB-HCI patients can be successfully treated for active TB without extending treatment duration.

AB - The impact of hepatitis C virus infection (HCI), the most common bloodborne virus infection in the USA, on outcome of active tuberculosis (TB) treatment is largely unknown. We aimed to describe characteristics of TB patients with hepatitis C virus infection (TB-HCI) in King County, Washington, including TB treatment duration and outcome. We reviewed 1510 records of patients treated for active TB at the Public Health - Seattle & King County Tuberculosis Control Program between 2000 and 2010, and identified 53 with HCI. Advanced age, being born in the USA, HIV infection, homelessness and injection drug use were independently associated with HCI in TB cases. Independent factors associated with increased treatment duration included HIV infection, excess alcohol use, extrapulmonary TB, and any drug-resistant TB disease. Our findings suggest that TB-HCI patients can be successfully treated for active TB without extending treatment duration.

KW - Hepatitis C

KW - tuberculosis (TB)

UR - http://www.scopus.com/inward/record.url?scp=84901464188&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84901464188&partnerID=8YFLogxK

U2 - 10.1017/S0950268813002355

DO - 10.1017/S0950268813002355

M3 - Article

C2 - 24067406

AN - SCOPUS:84901464188

VL - 142

SP - 1459

EP - 1466

JO - Epidemiology and Infection

JF - Epidemiology and Infection

SN - 0950-2688

IS - 7

ER -