Characterization of hepatitis C infection in tuberculosis patients in an urban city in the USA

M. Campo, A. Shrestha, E. Oren, H. Thiede, J. Duchin, M. Narita, K. Crothers

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The impact of hepatitis C virus infection (HCI), the most common bloodborne virus infection in the USA, on outcome of active tuberculosis (TB) treatment is largely unknown. We aimed to describe characteristics of TB patients with hepatitis C virus infection (TB-HCI) in King County, Washington, including TB treatment duration and outcome. We reviewed 1510 records of patients treated for active TB at the Public Health - Seattle & King County Tuberculosis Control Program between 2000 and 2010, and identified 53 with HCI. Advanced age, being born in the USA, HIV infection, homelessness and injection drug use were independently associated with HCI in TB cases. Independent factors associated with increased treatment duration included HIV infection, excess alcohol use, extrapulmonary TB, and any drug-resistant TB disease. Our findings suggest that TB-HCI patients can be successfully treated for active TB without extending treatment duration.

Original languageEnglish (US)
Pages (from-to)1459-1466
Number of pages8
JournalEpidemiology and infection
Volume142
Issue number7
DOIs
StatePublished - Jul 2014
Externally publishedYes

Keywords

  • Hepatitis C
  • tuberculosis (TB)

ASJC Scopus subject areas

  • Epidemiology
  • Infectious Diseases

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