Chemistry and Materials Science have been studied in the same buildings at the University of Arizona for over 70 years. In this time, some substances in common use have been found to be hazardous, while many new substances have come into use, sometimes without studies to determine long term health effects. This project seeks to develop methodology to examine and compare the accumulation of chemicals in student workspaces and laboratories at the University of Arizona. This Project has used a variety of analytical techniques, including x-ray fluorescence, and energy dispersive spectroscopy to analyze samples from laboratory spaces such as: sink drains, countertops, fume hoods, and air filters to determine substances students could contact. These methods have identified contamination from mercury, chromium, and lead, among other substances present in student laboratories. Identification of these toxins is an important step in improving laboratory safety.