Chemical measurements in Drosophila

Monique A. Makos, Nicholas J. Kuklinski, Michael L. Heien, E. Carina Berglund, Andrew G. Ewing

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations


The fruit fly, Drosophila melanogaster, has been extensively used as a model organism in genetics research and has significantly contributed to understanding molecular, cellular and evolutionary aspects of human behavior. Recently, research has focused on developing analytical methods to obtain highly sensitive chemical quantification along with spatiotemporal information from Drosophila melanogaster. We review a number of these advances in capillary electrophoresis, high-performance liquid chromatography, mass spectrometry, and technologies involving intact organisms, including in vivo electrochemistry.

Original languageEnglish (US)
Pages (from-to)1223-1234
Number of pages12
JournalTrAC - Trends in Analytical Chemistry
Issue number11
StatePublished - 2009
Externally publishedYes


  • Capillary electrophoresis
  • Drosophila
  • Embryo
  • High-performance liquid chromatography
  • Larvae
  • MEMS-based system
  • Mass spectrometry
  • Micellar electrokinetic chromatography
  • Microfluidics
  • in vivo electrochemistry

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy


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