Chemical measurements in Drosophila

Monique A. Makos, Nicholas J. Kuklinski, Michael L. Heien, E. Carina Berglund, Andrew G. Ewing

Research output: Contribution to journalReview article

4 Scopus citations

Abstract

The fruit fly, Drosophila melanogaster, has been extensively used as a model organism in genetics research and has significantly contributed to understanding molecular, cellular and evolutionary aspects of human behavior. Recently, research has focused on developing analytical methods to obtain highly sensitive chemical quantification along with spatiotemporal information from Drosophila melanogaster. We review a number of these advances in capillary electrophoresis, high-performance liquid chromatography, mass spectrometry, and technologies involving intact organisms, including in vivo electrochemistry.

Original languageEnglish (US)
Pages (from-to)1223-1234
Number of pages12
JournalTrAC - Trends in Analytical Chemistry
Volume28
Issue number11
DOIs
StatePublished - Jan 1 2009

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Keywords

  • Capillary electrophoresis
  • Drosophila
  • Embryo
  • High-performance liquid chromatography
  • Larvae
  • MEMS-based system
  • Mass spectrometry
  • Micellar electrokinetic chromatography
  • Microfluidics
  • in vivo electrochemistry

ASJC Scopus subject areas

  • Analytical Chemistry
  • Spectroscopy

Cite this

Makos, M. A., Kuklinski, N. J., Heien, M. L., Berglund, E. C., & Ewing, A. G. (2009). Chemical measurements in Drosophila. TrAC - Trends in Analytical Chemistry, 28(11), 1223-1234. https://doi.org/10.1016/j.trac.2009.08.005