Thomas P. Miller, Stephen E. Jones

Research output: Contribution to journalArticlepeer-review

57 Scopus citations


22 patients with localised (stage I or II) diffuse lymphoma were treated with chemotherapy at the time of diagnosis. 14 patients received chemotherapy as the only treatment, and 8 received chemotherapy plus local irradiation. Doxorubicin-containing drug regimens were used in 20 patients. All 22 patients achieved a complete remission and remain alive with a median survival from the time of diagnosis of 27+ months. 21 patients (95%) have remained continuously free of disease with a median disease-free survival from the completion of chemotherapy of 23+ months. These findings provide a strong rationale for further clinical trials of chemotherapy alone or chemotherapy followed by regional radiotherapy for localised stages of diffuse lymphoma.

Original languageEnglish (US)
Pages (from-to)358-360
Number of pages3
JournalThe Lancet
Issue number8112
StatePublished - Feb 17 1979

ASJC Scopus subject areas

  • Medicine(all)

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