Chloriolins A‒C, Chlorinated Sesquiterpenes Produced by Fungal Cultures Separated from a Jaspis Marine Sponge

Xing Chung Cheng, Mustafa Varoglu, Leif Abrell, Phillip Crews, Emil Lobkovsky, Jon Clardy

Research output: Contribution to journalArticle

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Three new chlorinated, cyclic sesquiterpenes, chloriolin A (1), B (2), C (3), and two known compounds, coriolin B (4) and dihydrocoriolin C (5), were isolated from an unidentified fungus which was initially separated from the marine sponge Jaspis aff. johnstoni and then cultured on marine media. 2D NMR experiments, synthetic transformations, and X-ray crystallography were used to establish the structures of the new compounds.

Original languageEnglish (US)
Pages (from-to)6344-6348
Number of pages5
JournalJournal of Organic Chemistry
Issue number21
StatePublished - Oct 1 1994


ASJC Scopus subject areas

  • Organic Chemistry

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