Chronic lymphocytic leukemia in young adults

Catherine S Perry, C. R. Kjeldsberg, D. R. Head, K. C. DiFiore, B. Tudor

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The occurrence of chronic lymphocytic leukemia (CLL), B-cell type, is thought to be distinctly uncommon in patients younger than 40 years of age. Previous case reports of CLL in young adults and children were published before the widespread use of immunologic surface markers in the diagnosis of lymphoproliferative disorders. The authors report four patients with B-cell CLL, all diagnosed with the aid of immunologic markers. The patients were 30 years of age or younger at the time of diagnosis. Their subsequent course has been similar to B-cell CLL in the older age group: one is alive without progression of disease 30 months after diagnosis; one has shown progession of the disease but is alive, after chemotherapy, 36 months after diagnosis; while the other two had continued progression of disease and died, one at six and a half years and the other at 14 months, after diagnosis. The occurrence of B-cell CLL in young adults and its potential implications are discussed.

Original languageEnglish (US)
Pages (from-to)675-678
Number of pages4
JournalAmerican Journal of Clinical Pathology
Volume84
Issue number5
StatePublished - 1985
Externally publishedYes

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B-Cell Chronic Lymphocytic Leukemia
Young Adult
Disease Progression
Lymphoproliferative Disorders
Surface Antigens
Age Groups
Biomarkers
Drug Therapy

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Perry, C. S., Kjeldsberg, C. R., Head, D. R., DiFiore, K. C., & Tudor, B. (1985). Chronic lymphocytic leukemia in young adults. American Journal of Clinical Pathology, 84(5), 675-678.

Chronic lymphocytic leukemia in young adults. / Perry, Catherine S; Kjeldsberg, C. R.; Head, D. R.; DiFiore, K. C.; Tudor, B.

In: American Journal of Clinical Pathology, Vol. 84, No. 5, 1985, p. 675-678.

Research output: Contribution to journalArticle

Perry, CS, Kjeldsberg, CR, Head, DR, DiFiore, KC & Tudor, B 1985, 'Chronic lymphocytic leukemia in young adults', American Journal of Clinical Pathology, vol. 84, no. 5, pp. 675-678.
Perry CS, Kjeldsberg CR, Head DR, DiFiore KC, Tudor B. Chronic lymphocytic leukemia in young adults. American Journal of Clinical Pathology. 1985;84(5):675-678.
Perry, Catherine S ; Kjeldsberg, C. R. ; Head, D. R. ; DiFiore, K. C. ; Tudor, B. / Chronic lymphocytic leukemia in young adults. In: American Journal of Clinical Pathology. 1985 ; Vol. 84, No. 5. pp. 675-678.
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