Circadian rhythm of synaptic excitability in rat and monkey central nervous system

C. A. Barnes, B. L. Mcnaughton, G. V. Goddard, R. M. Douglas, R. Adamec

Research output: Contribution to journalArticlepeer-review

105 Scopus citations

Abstract

Synaptic responses in hippocampal granule cells to stimulation of their afferent fibers from the entorhinal cortex fluctuate with a 24-hour period. The phase of this cycle for rats and monkeys depends on whether the animal is naturally nocturnal or diurnal. In a rat blinded by enucleation, the rhythm persists but drifts out of phase with the rhythm of sighted controls.

Original languageEnglish (US)
Pages (from-to)91-92
Number of pages2
JournalScience
Volume197
Issue number4298
DOIs
StatePublished - Jan 1 1977
Externally publishedYes

ASJC Scopus subject areas

  • General

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