Circadian rhythms in Neurospora crassa: Oligomycin-resistant mutations affect periodicity

Carol Dieckmann, Stuart Brody

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

Nuclear mutations conferring resistance to oligomycin, a mitochondrial inhibitor, shorten the period of the circadian conidiation rhythm of Neurospora crassa from the normal 21.5 hours to 18 to 19 hours and slow the linear growth rate by 30 percent. These olir mutations map very close to frq, a locus at which mutations affecting periodicity have been previously obtained. The possibilities are discussed that mitochondria are involved in circadian rhythm generation and that certain period-length mutations affect mitochondrial functions.

Original languageEnglish (US)
Pages (from-to)896-898
Number of pages3
JournalScience
Volume207
Issue number4433
StatePublished - Jan 1 1980
Externally publishedYes

ASJC Scopus subject areas

  • General

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