Classification learning in Alzheimer's disease

Szabolcs Kéri, János Kálmán, Steven Z Rapcsak, Andrea Antal, György Benedek, Zoltán Janka

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Previous research has demonstrated that explicit recognition of dot patterns is impaired in amnesic patients with damage to the limbic-diencephalic memory system, while implicit categorization of the same kind of stimuli is preserved. The aim of the present study was to investigate the relationship between recognition and categorization performances in patients with Alzheimer's disease. Consistent with the findings in amnesic subjects, our results revealed that the explicit recognition of dot patterns was significantly impaired in Alzheimer's disease. However, implicit categorization functions were also disrupted. This was selective for the prototype stimuli; the categorization of non-prototype dot patterns was spared. The impaired category learning is likely to reflect the damage of modality-specific neocortical areas in Alzheimer's disease.

Original languageEnglish (US)
Pages (from-to)1063-1068
Number of pages6
JournalBrain
Volume122
Issue number6
DOIs
StatePublished - Jun 1999

Fingerprint

Alzheimer Disease
Learning
Research
Recognition (Psychology)

Keywords

  • Alzheimer's disease
  • Classification learning
  • Non-declarative memory
  • Prototype

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Kéri, S., Kálmán, J., Rapcsak, S. Z., Antal, A., Benedek, G., & Janka, Z. (1999). Classification learning in Alzheimer's disease. Brain, 122(6), 1063-1068. https://doi.org/10.1093/brain/122.6.1063

Classification learning in Alzheimer's disease. / Kéri, Szabolcs; Kálmán, János; Rapcsak, Steven Z; Antal, Andrea; Benedek, György; Janka, Zoltán.

In: Brain, Vol. 122, No. 6, 06.1999, p. 1063-1068.

Research output: Contribution to journalArticle

Kéri, S, Kálmán, J, Rapcsak, SZ, Antal, A, Benedek, G & Janka, Z 1999, 'Classification learning in Alzheimer's disease', Brain, vol. 122, no. 6, pp. 1063-1068. https://doi.org/10.1093/brain/122.6.1063
Kéri S, Kálmán J, Rapcsak SZ, Antal A, Benedek G, Janka Z. Classification learning in Alzheimer's disease. Brain. 1999 Jun;122(6):1063-1068. https://doi.org/10.1093/brain/122.6.1063
Kéri, Szabolcs ; Kálmán, János ; Rapcsak, Steven Z ; Antal, Andrea ; Benedek, György ; Janka, Zoltán. / Classification learning in Alzheimer's disease. In: Brain. 1999 ; Vol. 122, No. 6. pp. 1063-1068.
@article{2b0637340fd440b3b926161c59fcfbba,
title = "Classification learning in Alzheimer's disease",
abstract = "Previous research has demonstrated that explicit recognition of dot patterns is impaired in amnesic patients with damage to the limbic-diencephalic memory system, while implicit categorization of the same kind of stimuli is preserved. The aim of the present study was to investigate the relationship between recognition and categorization performances in patients with Alzheimer's disease. Consistent with the findings in amnesic subjects, our results revealed that the explicit recognition of dot patterns was significantly impaired in Alzheimer's disease. However, implicit categorization functions were also disrupted. This was selective for the prototype stimuli; the categorization of non-prototype dot patterns was spared. The impaired category learning is likely to reflect the damage of modality-specific neocortical areas in Alzheimer's disease.",
keywords = "Alzheimer's disease, Classification learning, Non-declarative memory, Prototype",
author = "Szabolcs K{\'e}ri and J{\'a}nos K{\'a}lm{\'a}n and Rapcsak, {Steven Z} and Andrea Antal and Gy{\"o}rgy Benedek and Zolt{\'a}n Janka",
year = "1999",
month = "6",
doi = "10.1093/brain/122.6.1063",
language = "English (US)",
volume = "122",
pages = "1063--1068",
journal = "Brain",
issn = "0006-8950",
publisher = "Oxford University Press",
number = "6",

}

TY - JOUR

T1 - Classification learning in Alzheimer's disease

AU - Kéri, Szabolcs

AU - Kálmán, János

AU - Rapcsak, Steven Z

AU - Antal, Andrea

AU - Benedek, György

AU - Janka, Zoltán

PY - 1999/6

Y1 - 1999/6

N2 - Previous research has demonstrated that explicit recognition of dot patterns is impaired in amnesic patients with damage to the limbic-diencephalic memory system, while implicit categorization of the same kind of stimuli is preserved. The aim of the present study was to investigate the relationship between recognition and categorization performances in patients with Alzheimer's disease. Consistent with the findings in amnesic subjects, our results revealed that the explicit recognition of dot patterns was significantly impaired in Alzheimer's disease. However, implicit categorization functions were also disrupted. This was selective for the prototype stimuli; the categorization of non-prototype dot patterns was spared. The impaired category learning is likely to reflect the damage of modality-specific neocortical areas in Alzheimer's disease.

AB - Previous research has demonstrated that explicit recognition of dot patterns is impaired in amnesic patients with damage to the limbic-diencephalic memory system, while implicit categorization of the same kind of stimuli is preserved. The aim of the present study was to investigate the relationship between recognition and categorization performances in patients with Alzheimer's disease. Consistent with the findings in amnesic subjects, our results revealed that the explicit recognition of dot patterns was significantly impaired in Alzheimer's disease. However, implicit categorization functions were also disrupted. This was selective for the prototype stimuli; the categorization of non-prototype dot patterns was spared. The impaired category learning is likely to reflect the damage of modality-specific neocortical areas in Alzheimer's disease.

KW - Alzheimer's disease

KW - Classification learning

KW - Non-declarative memory

KW - Prototype

UR - http://www.scopus.com/inward/record.url?scp=0345533867&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0345533867&partnerID=8YFLogxK

U2 - 10.1093/brain/122.6.1063

DO - 10.1093/brain/122.6.1063

M3 - Article

C2 - 10356059

AN - SCOPUS:0345533867

VL - 122

SP - 1063

EP - 1068

JO - Brain

JF - Brain

SN - 0006-8950

IS - 6

ER -