Clinical and translational potential of MRI evaluation in knee osteoarthritis

Daichi Hayashi, Ali Guermazi, C. Kent Kwoh

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Magnetic resonance imaging (MRI) has become an increasingly important imaging technique in osteoarthritis (OA) research, and is widely used in the ongoing endeavor to understand the pathogenesis of OA and to develop structure and disease-modifying OA drugs. MRI offers semiquantitative, quantitative and compositional evaluation of knee OA, and enables visualization of tissues that are not seen by radiography, including but not limited to cartilage, meniscus, bone marrow lesions, synovitis, and muscles. It is now recognized that contrast-enhanced MRI enables more accurate evaluation of synovitis than MRI without contrast. Because of its ability to visualize multiple pain-related tissue pathology in three dimensions, MRI is the best modality for imaging of OA.

Original languageEnglish (US)
Article number391
JournalCurrent rheumatology reports
Volume16
Issue number1
DOIs
StatePublished - Jan 1 2014

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Keywords

  • Bone marrow lesion
  • Cartilage
  • Knee
  • MRI
  • MRI evaluation
  • Magnetic resonance imaging
  • Meniscal root
  • Meniscus
  • Osteoarthritis
  • Quantitative
  • Radiography
  • Semiquantitative
  • Synovitis

ASJC Scopus subject areas

  • Rheumatology

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