Clinical and translational potential of MRI evaluation in knee osteoarthritis

Daichi Hayashi, Ali Guermazi, Chian K Kwoh

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Magnetic resonance imaging (MRI) has become an increasingly important imaging technique in osteoarthritis (OA) research, and is widely used in the ongoing endeavor to understand the pathogenesis of OA and to develop structure and disease-modifying OA drugs. MRI offers semiquantitative, quantitative and compositional evaluation of knee OA, and enables visualization of tissues that are not seen by radiography, including but not limited to cartilage, meniscus, bone marrow lesions, synovitis, and muscles. It is now recognized that contrast-enhanced MRI enables more accurate evaluation of synovitis than MRI without contrast. Because of its ability to visualize multiple pain-related tissue pathology in three dimensions, MRI is the best modality for imaging of OA.

Original languageEnglish (US)
Article number391
JournalCurrent Rheumatology Reports
Volume16
Issue number1
DOIs
StatePublished - Jan 2014

Fingerprint

Knee Osteoarthritis
Osteoarthritis
Magnetic Resonance Imaging
Synovitis
Nociceptive Pain
Radiography
Cartilage
Bone Marrow
Pathology
Muscles
Research
Pharmaceutical Preparations

Keywords

  • Bone marrow lesion
  • Cartilage
  • Knee
  • Magnetic resonance imaging
  • Meniscal root
  • Meniscus
  • MRI
  • MRI evaluation
  • Osteoarthritis
  • Quantitative
  • Radiography
  • Semiquantitative
  • Synovitis

ASJC Scopus subject areas

  • Rheumatology

Cite this

Clinical and translational potential of MRI evaluation in knee osteoarthritis. / Hayashi, Daichi; Guermazi, Ali; Kwoh, Chian K.

In: Current Rheumatology Reports, Vol. 16, No. 1, 391, 01.2014.

Research output: Contribution to journalArticle

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