Clinical outcomes associated with sleep-disordered breathing in Caucasian and Hispanic children - The Tucson Children's Assessment of Sleep Apnea Study (TuCASA)

James L. Goodwin, Kris L. Kaemingk, Ralph F Fregosi, Gerald M. Rosen, Wayne J Morgan, Duane L Sherrill, Stuart F Quan

Research output: Contribution to journalArticle

104 Citations (Scopus)

Abstract

Study Objectives: This report describes clinical outcomes and threshold levels of respiratory disturbance index (RDI) associated with sleep-disordered breathing in children participating in the Tucson Children's Assessment of Sleep Apnea study. Design: A community-based, prospective cohort study designed to assess the severity of sleep-related symptoms associated with sleep-disordered breathing in children aged 6 to 11 years. Setting: Students attending elementary school in the Tucson Unified School District. Participants: Unattended home polysomnograms were completed on 239 children - 55.2% boys, 51% Hispanic, and 55% between the ages of 6 and 8 years. Measurements and Results: Based on full home polysomnography, levels of RDI that correspond to a higher prevalence of clinical symptoms of sleep-disordered breathing in children aged 6 to 11 were observed. An RDI of at least 5 was associated with frequent snoring (20.3% vs 9.1%, P< .01), excessive daytime sleepiness (22.9% vs 10.7%, P< .01), and learning problems (8.5% vs 2.5%, P< .04) when no oxygen desaturation accompanied the respiratory event. An RDI of at least 1 was associated with these symptoms when a 3% oxygen desaturation was required, snoring (24.0% vs 10.4%, P<.006), excessive daytime sleepiness (24.0% vs 13.4%, P<.04), and learning problems (10.7% vs 3.0%, P<02). Hispanic or Caucasian ethnicity, sex, age category, obesity, insomnia, and witnessed apnea were not associated with RDI regardless of event definition. Conclusions: The Tucson Children's Assessment of Sleep Apnea study has shown that there are values of RDI based on polysomnography that correspond to an increased rate of clinical symptoms in children ages 6 to 11 years.

Original languageEnglish (US)
Pages (from-to)587-591
Number of pages5
JournalSleep
Volume26
Issue number5
StatePublished - Aug 1 2003

Fingerprint

Sleep Apnea Syndromes
Hispanic Americans
Snoring
Polysomnography
Learning
Oxygen
Sleep Initiation and Maintenance Disorders
Apnea
Sleep
Cohort Studies
Obesity
Prospective Studies
Students

Keywords

  • Children
  • RDI
  • Sleep
  • Sleep apnea
  • Sleep-disordered breathing

ASJC Scopus subject areas

  • Physiology

Cite this

@article{c41a2489fbe94215af535935cabbd23b,
title = "Clinical outcomes associated with sleep-disordered breathing in Caucasian and Hispanic children - The Tucson Children's Assessment of Sleep Apnea Study (TuCASA)",
abstract = "Study Objectives: This report describes clinical outcomes and threshold levels of respiratory disturbance index (RDI) associated with sleep-disordered breathing in children participating in the Tucson Children's Assessment of Sleep Apnea study. Design: A community-based, prospective cohort study designed to assess the severity of sleep-related symptoms associated with sleep-disordered breathing in children aged 6 to 11 years. Setting: Students attending elementary school in the Tucson Unified School District. Participants: Unattended home polysomnograms were completed on 239 children - 55.2{\%} boys, 51{\%} Hispanic, and 55{\%} between the ages of 6 and 8 years. Measurements and Results: Based on full home polysomnography, levels of RDI that correspond to a higher prevalence of clinical symptoms of sleep-disordered breathing in children aged 6 to 11 were observed. An RDI of at least 5 was associated with frequent snoring (20.3{\%} vs 9.1{\%}, P< .01), excessive daytime sleepiness (22.9{\%} vs 10.7{\%}, P< .01), and learning problems (8.5{\%} vs 2.5{\%}, P< .04) when no oxygen desaturation accompanied the respiratory event. An RDI of at least 1 was associated with these symptoms when a 3{\%} oxygen desaturation was required, snoring (24.0{\%} vs 10.4{\%}, P<.006), excessive daytime sleepiness (24.0{\%} vs 13.4{\%}, P<.04), and learning problems (10.7{\%} vs 3.0{\%}, P<02). Hispanic or Caucasian ethnicity, sex, age category, obesity, insomnia, and witnessed apnea were not associated with RDI regardless of event definition. Conclusions: The Tucson Children's Assessment of Sleep Apnea study has shown that there are values of RDI based on polysomnography that correspond to an increased rate of clinical symptoms in children ages 6 to 11 years.",
keywords = "Children, RDI, Sleep, Sleep apnea, Sleep-disordered breathing",
author = "Goodwin, {James L.} and Kaemingk, {Kris L.} and Fregosi, {Ralph F} and Rosen, {Gerald M.} and Morgan, {Wayne J} and Sherrill, {Duane L} and Quan, {Stuart F}",
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journal = "Sleep",
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T1 - Clinical outcomes associated with sleep-disordered breathing in Caucasian and Hispanic children - The Tucson Children's Assessment of Sleep Apnea Study (TuCASA)

AU - Goodwin, James L.

AU - Kaemingk, Kris L.

AU - Fregosi, Ralph F

AU - Rosen, Gerald M.

AU - Morgan, Wayne J

AU - Sherrill, Duane L

AU - Quan, Stuart F

PY - 2003/8/1

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N2 - Study Objectives: This report describes clinical outcomes and threshold levels of respiratory disturbance index (RDI) associated with sleep-disordered breathing in children participating in the Tucson Children's Assessment of Sleep Apnea study. Design: A community-based, prospective cohort study designed to assess the severity of sleep-related symptoms associated with sleep-disordered breathing in children aged 6 to 11 years. Setting: Students attending elementary school in the Tucson Unified School District. Participants: Unattended home polysomnograms were completed on 239 children - 55.2% boys, 51% Hispanic, and 55% between the ages of 6 and 8 years. Measurements and Results: Based on full home polysomnography, levels of RDI that correspond to a higher prevalence of clinical symptoms of sleep-disordered breathing in children aged 6 to 11 were observed. An RDI of at least 5 was associated with frequent snoring (20.3% vs 9.1%, P< .01), excessive daytime sleepiness (22.9% vs 10.7%, P< .01), and learning problems (8.5% vs 2.5%, P< .04) when no oxygen desaturation accompanied the respiratory event. An RDI of at least 1 was associated with these symptoms when a 3% oxygen desaturation was required, snoring (24.0% vs 10.4%, P<.006), excessive daytime sleepiness (24.0% vs 13.4%, P<.04), and learning problems (10.7% vs 3.0%, P<02). Hispanic or Caucasian ethnicity, sex, age category, obesity, insomnia, and witnessed apnea were not associated with RDI regardless of event definition. Conclusions: The Tucson Children's Assessment of Sleep Apnea study has shown that there are values of RDI based on polysomnography that correspond to an increased rate of clinical symptoms in children ages 6 to 11 years.

AB - Study Objectives: This report describes clinical outcomes and threshold levels of respiratory disturbance index (RDI) associated with sleep-disordered breathing in children participating in the Tucson Children's Assessment of Sleep Apnea study. Design: A community-based, prospective cohort study designed to assess the severity of sleep-related symptoms associated with sleep-disordered breathing in children aged 6 to 11 years. Setting: Students attending elementary school in the Tucson Unified School District. Participants: Unattended home polysomnograms were completed on 239 children - 55.2% boys, 51% Hispanic, and 55% between the ages of 6 and 8 years. Measurements and Results: Based on full home polysomnography, levels of RDI that correspond to a higher prevalence of clinical symptoms of sleep-disordered breathing in children aged 6 to 11 were observed. An RDI of at least 5 was associated with frequent snoring (20.3% vs 9.1%, P< .01), excessive daytime sleepiness (22.9% vs 10.7%, P< .01), and learning problems (8.5% vs 2.5%, P< .04) when no oxygen desaturation accompanied the respiratory event. An RDI of at least 1 was associated with these symptoms when a 3% oxygen desaturation was required, snoring (24.0% vs 10.4%, P<.006), excessive daytime sleepiness (24.0% vs 13.4%, P<.04), and learning problems (10.7% vs 3.0%, P<02). Hispanic or Caucasian ethnicity, sex, age category, obesity, insomnia, and witnessed apnea were not associated with RDI regardless of event definition. Conclusions: The Tucson Children's Assessment of Sleep Apnea study has shown that there are values of RDI based on polysomnography that correspond to an increased rate of clinical symptoms in children ages 6 to 11 years.

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