Clinical results with acridine orange using a novel confocal laparoscope

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We previously reported on the development of a multi-spectral confocal laparoscope for clinical imaging. In this paper we present current results using the system to image ovaries with a new laparoscope design using the contrast agent acridine orange. This new laparoscope integrates computer controlled systems for focus, depth scans, and localized contrast agent delivery. Precise axial position control is accomplished with tiny stepper motors integrated inside the laparoscope handle. Ergonomic handle controls allow for data acquisition, deliver of contrast agents, and adjustment of imaging depth during procedures by the surgeon. We have approval to use acridine orange in our clinical trials to image ovaries in vivo during oophorectomies. We present in vivo results using both acridine orange and fluorescein as the topically administered contrast agent.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7172
DOIs
StatePublished - 2009
EventEndoscopic Microscopy IV - San Jose, CA, United States
Duration: Jan 25 2009Jan 26 2009

Other

OtherEndoscopic Microscopy IV
CountryUnited States
CitySan Jose, CA
Period1/25/091/26/09

Fingerprint

Laparoscopy
Laparoscopes
Acridine Orange
Contrast Media
ovaries
Ovary
human factors engineering
Social Adjustment
surgeons
Human Engineering
Computer Systems
Medical imaging
Position control
Ovariectomy
Ergonomics
Fluorescein
data acquisition
Data acquisition
delivery
adjusting

Keywords

  • Acridine orange
  • Clinical trials
  • Confocal
  • Endoscope
  • Fluorescein
  • Laparoscope
  • Microscopy
  • Ovarian cancer

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Tanbakuchi, A. A., Rouse, A. R., Hatch, K. D., & Gmitro, A. F. (2009). Clinical results with acridine orange using a novel confocal laparoscope. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 7172). [71720H] https://doi.org/10.1117/12.809540

Clinical results with acridine orange using a novel confocal laparoscope. / Tanbakuchi, Anthony A.; Rouse, Andrew R; Hatch, Kenneth D; Gmitro, Arthur F.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7172 2009. 71720H.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tanbakuchi, AA, Rouse, AR, Hatch, KD & Gmitro, AF 2009, Clinical results with acridine orange using a novel confocal laparoscope. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 7172, 71720H, Endoscopic Microscopy IV, San Jose, CA, United States, 1/25/09. https://doi.org/10.1117/12.809540
Tanbakuchi AA, Rouse AR, Hatch KD, Gmitro AF. Clinical results with acridine orange using a novel confocal laparoscope. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7172. 2009. 71720H https://doi.org/10.1117/12.809540
Tanbakuchi, Anthony A. ; Rouse, Andrew R ; Hatch, Kenneth D ; Gmitro, Arthur F. / Clinical results with acridine orange using a novel confocal laparoscope. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7172 2009.
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