Clinical stage I endometrial carcinoma: Pitfalls in preoperative assessment with MR imaging: Work in progress

Leslie M. Scoutt, Shirley M. McCarthy, Stuart D Flynn, Robert C. Lange, Fred Long, Robert C. Smith, Setsuko K Chambers, Ernest Kohorn, Peter Schwartz, Joseph T. Chambers

Research output: Contribution to journalArticle

94 Citations (Scopus)

Abstract

PURPOSE: To identify potential pitfalls in using magnetic resonance (MR) imaging to determine the depth of myometrial invasion in patients with clinical stage I endometrial carcinoma. MATERIALS AND METHODS: Forty women with clinical stage I endometrial carcinoma underwent preoperative pelvic MR imaging. Uterine length, tumor signal intensity, appearance of the junctional zone, presence of large polypoid tumors, leiomyomata, and congenital uterine anomalies were analyzed. Univariate logistic-regression analysis was performed to identify associations between incorrect MR staging and these variables. RESULTS: MR staging of IA, IB, and IC disease was 55% accurate (22 of 40 cases); MR differentiation of deep myometrial invasion (stage IC) from superficial disease (stages IA and IB) was 78% accurate (31 of 40 cases). Older age (P = .025), presence of polypoid tumors (P = .025), and difficulty in pathologic staging (P < .005) were significantly associated with incorrect MR assessment. CONCLUSION: When present, large polypoid tumors, leiomyomata, congenital anomalies, small uteri, and indistinct zonal anatomy may make it difficult to assess myometrial invasion at MR imaging.

Original languageEnglish (US)
Pages (from-to)567-572
Number of pages6
JournalRadiology
Volume194
Issue number2
StatePublished - Feb 1995
Externally publishedYes

Fingerprint

Endometrial Neoplasms
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
Leiomyoma
Neoplasms
Uterus
Anatomy
Logistic Models
Regression Analysis

Keywords

  • Uterine neoplasms, staging, 854.1214, 854.315, 854.324, 854.329
  • Uterus, endometrium, 854.1214, 854.14782, 854.14789, 854.315
  • Uterus, myometrium, 854.1214, 854.14782, 854.14789, 854.315

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Scoutt, L. M., McCarthy, S. M., Flynn, S. D., Lange, R. C., Long, F., Smith, R. C., ... Chambers, J. T. (1995). Clinical stage I endometrial carcinoma: Pitfalls in preoperative assessment with MR imaging: Work in progress. Radiology, 194(2), 567-572.

Clinical stage I endometrial carcinoma : Pitfalls in preoperative assessment with MR imaging: Work in progress. / Scoutt, Leslie M.; McCarthy, Shirley M.; Flynn, Stuart D; Lange, Robert C.; Long, Fred; Smith, Robert C.; Chambers, Setsuko K; Kohorn, Ernest; Schwartz, Peter; Chambers, Joseph T.

In: Radiology, Vol. 194, No. 2, 02.1995, p. 567-572.

Research output: Contribution to journalArticle

Scoutt, LM, McCarthy, SM, Flynn, SD, Lange, RC, Long, F, Smith, RC, Chambers, SK, Kohorn, E, Schwartz, P & Chambers, JT 1995, 'Clinical stage I endometrial carcinoma: Pitfalls in preoperative assessment with MR imaging: Work in progress', Radiology, vol. 194, no. 2, pp. 567-572.
Scoutt LM, McCarthy SM, Flynn SD, Lange RC, Long F, Smith RC et al. Clinical stage I endometrial carcinoma: Pitfalls in preoperative assessment with MR imaging: Work in progress. Radiology. 1995 Feb;194(2):567-572.
Scoutt, Leslie M. ; McCarthy, Shirley M. ; Flynn, Stuart D ; Lange, Robert C. ; Long, Fred ; Smith, Robert C. ; Chambers, Setsuko K ; Kohorn, Ernest ; Schwartz, Peter ; Chambers, Joseph T. / Clinical stage I endometrial carcinoma : Pitfalls in preoperative assessment with MR imaging: Work in progress. In: Radiology. 1995 ; Vol. 194, No. 2. pp. 567-572.
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