Clinicopathological findings of solid pseudopapillary neoplasm in a 10-year-old girl presenting with pruritus, a case report and concise review

Sarah K. Daley, Neha Varshney, Peter Wanes, Achyut K. Bhattacharyya, Ghassan A. Tranesh

Research output: Contribution to journalArticlepeer-review

Abstract

Solid pseudopapillary neoplasms (SPNs) are rare cystic lesions with low malignant potential making up approximately 2–3% of all primary pancreatic neoplasms in both pediatric and adult patients combined. While malignant pancreatic tumors are extremely rare in children, SPNs are one of the more common pancreatic neoplasms in this age group. Although most SPNs have a benign course with excellent long-term prognosis, they do have the potential to behave aggressively. Most children with SPN present with a palpable abdominal mass or abdominal pain. Here we describe an unusual presentation of SPN in a pediatric patient who did not have either of these findings but instead presented only with a two-month history of pruritus. We incorporate clinical, imaging, cytologic, and histologic data to make an accurate diagnosis of SPN in a 10-year-old female with an unusual presentation. Review of the literature failed to find a similar presentation of this tumor.

Original languageEnglish (US)
Article number200449
JournalHuman Pathology: Case Reports
Volume22
DOIs
StatePublished - Nov 2020

Keywords

  • Cystic lesion of the pancreas
  • Pancreas
  • Pancreatic tumor
  • Pediatric pancreatic neoplasm
  • SPN
  • Solid pseudopapillary neoplasm
  • Solid pseudopapillary tumor

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Fingerprint

Dive into the research topics of 'Clinicopathological findings of solid pseudopapillary neoplasm in a 10-year-old girl presenting with pruritus, a case report and concise review'. Together they form a unique fingerprint.

Cite this