Clostridium difficile infection an overview of the disease and its pathogenesis, epidemiology and interventions

Research output: Contribution to journalArticle

68 Scopus citations

Abstract

Clostridium difficile infection (CDI) is the primary cause of antibiotic-associated diarrhea and is a significant nosocomial disease. In the past ten years, variant toxin-producing strains of C. difficile have emerged, that have been associated with severe disease as well as outbreaks worldwide. This review summarizes current information on C. difficile pathogenesis and disease, and highlights interventions used to combat single and recurrent episodes of CDI.

Original languageEnglish (US)
Pages (from-to)234-242
Number of pages9
JournalGut microbes
Volume1
Issue number4
DOIs
StatePublished - 2010

Keywords

  • CDAD
  • CDI
  • Clostridium difficile
  • Hypervirulent
  • Infection
  • Infection control
  • Pathogenesis
  • Spore

ASJC Scopus subject areas

  • Microbiology
  • Gastroenterology
  • Microbiology (medical)
  • Infectious Diseases

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