Co-registered spectrally encoded confocal microscopy and optical frequency domain imaging system

D. K. Kang, M. J. Suter, C. Boudoux, P. S. Yachimski, W. P. Puricelli, N. S. Nishioka, M. Mino-Kenudson, G. Y. Lauwers, B. E. Bouma, G. J. Tearney

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Spectrally encoded confocal microscopy and optical frequency domain imaging are two non-contact optical imaging technologies that provide images of tissue cellular and architectural morphology, which are both used for histopathological diagnosis. Although spectrally encoded confocal microscopy has better transverse resolution than optical frequency domain imaging, optical frequency domain imaging can penetrate deeper into tissues, which potentially enables the visualization of different morphologic features. We have developed a co-registered spectrally encoded confocal microscopy and optical frequency domain imaging system and have obtained preliminary images from human oesophageal biopsy samples to compare the capabilities of these imaging techniques for diagnosing oesophageal pathology.

Original languageEnglish (US)
Pages (from-to)87-91
Number of pages5
JournalJournal of Microscopy
Volume239
Issue number2
DOIs
StatePublished - Aug 2010
Externally publishedYes

Keywords

  • Confocal microscopy
  • co-registered imaging
  • multi-modality imaging
  • optical coherence tomography

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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  • Cite this

    Kang, D. K., Suter, M. J., Boudoux, C., Yachimski, P. S., Puricelli, W. P., Nishioka, N. S., Mino-Kenudson, M., Lauwers, G. Y., Bouma, B. E., & Tearney, G. J. (2010). Co-registered spectrally encoded confocal microscopy and optical frequency domain imaging system. Journal of Microscopy, 239(2), 87-91. https://doi.org/10.1111/j.1365-2818.2010.03367.x