Abstract
Efficacy and safety of coaxial transthoracic fine-needle biopsy were evaluated in 54 patients with a history of malignant lymphoma and new chest lesions. Twenty-one patients had recurrent lymphoma. Correct diagnosis was made in 17 of the 21 patients (81%) after one biopsy. The sensitivity increased to 95% with repeat needle biopsy in three patients. Immunophenotyping (determining phenotype by means of immunologic examination) was essential for a definitive diagnosis of lymphoma in three patients. Non- lymphomatous malignancies were correctly diagnosed in 14 patients. An infectious organism was identified in 11 of 19 patients (58%) with benign lesions. Pneumothorax occurred in eight patients (15%), necessitating placement of a chest tube in two (4%). Mild hemoptysis was observed in four patients (7%). The authors conclude that coaxial transthoracic fine-needle biopsy in patients with a history of lymphoma is safe and accurate. The use of large cutting needles or surgical biopsy can be restricted to patients with false-negative findings at percutaneous biopsy and to patients in whom histologic transformation of lymphoma is suspected.
Original language | English (US) |
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Pages (from-to) | 175-178 |
Number of pages | 4 |
Journal | Radiology |
Volume | 183 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1 1992 |
Externally published | Yes |
Keywords
- Hodgkin disease, diagnosis
- Lung, biopsy
- Lymphatic system, biopsy
- Lymphoma, diagnosis
- Thorax, biopsy
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging