Coccidioidomycosis

D. A. Bronnimann, John N Galgiani

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Coccidioidomycosis is a largely self-limited fungal respiratory illness. However, the infrequent case of progressive or disseminated disease can be devastating. As international travel to and from endemic areas increases, physicians unfamiliar with the disease may be called upon to recognize and treat serious coccidioidal infections. The major risk factors for dissemination are race and immunosuppression. The most common sites of dissemination are the skin, lymph nodes, bone and meninges. Diagnosis is aided by investigation of the patient's clinical history, delayed-type hypersensitivity skin test reaction, serologic testing, and recovery of organisms from infected tissue or secretions for direct examination and culture. Fungicidal agents are not available, fortunately, fungistatic therapy allows many patients to recover. The availability of both intravenous/intrathecal and oral agents now allows more therapeutic flexibility in the treatment of this disease.

Original languageEnglish (US)
Pages (from-to)466-473
Number of pages8
JournalEuropean Journal of Clinical Microbiology & Infectious Diseases
Volume8
Issue number5
DOIs
StatePublished - May 1989

Fingerprint

Coccidioidomycosis
Meninges
Delayed Hypersensitivity
Skin Tests
Immunosuppression
Therapeutics
Lymph Nodes
Physicians
Bone and Bones
Skin
Infection

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology

Cite this

Coccidioidomycosis. / Bronnimann, D. A.; Galgiani, John N.

In: European Journal of Clinical Microbiology & Infectious Diseases, Vol. 8, No. 5, 05.1989, p. 466-473.

Research output: Contribution to journalArticle

@article{8cdfd7c7280d48e4841f3693495ee15a,
title = "Coccidioidomycosis",
abstract = "Coccidioidomycosis is a largely self-limited fungal respiratory illness. However, the infrequent case of progressive or disseminated disease can be devastating. As international travel to and from endemic areas increases, physicians unfamiliar with the disease may be called upon to recognize and treat serious coccidioidal infections. The major risk factors for dissemination are race and immunosuppression. The most common sites of dissemination are the skin, lymph nodes, bone and meninges. Diagnosis is aided by investigation of the patient's clinical history, delayed-type hypersensitivity skin test reaction, serologic testing, and recovery of organisms from infected tissue or secretions for direct examination and culture. Fungicidal agents are not available, fortunately, fungistatic therapy allows many patients to recover. The availability of both intravenous/intrathecal and oral agents now allows more therapeutic flexibility in the treatment of this disease.",
author = "Bronnimann, {D. A.} and Galgiani, {John N}",
year = "1989",
month = "5",
doi = "10.1007/BF01964061",
language = "English (US)",
volume = "8",
pages = "466--473",
journal = "European Journal of Clinical Microbiology and Infectious Diseases",
issn = "0934-9723",
publisher = "Springer Verlag",
number = "5",

}

TY - JOUR

T1 - Coccidioidomycosis

AU - Bronnimann, D. A.

AU - Galgiani, John N

PY - 1989/5

Y1 - 1989/5

N2 - Coccidioidomycosis is a largely self-limited fungal respiratory illness. However, the infrequent case of progressive or disseminated disease can be devastating. As international travel to and from endemic areas increases, physicians unfamiliar with the disease may be called upon to recognize and treat serious coccidioidal infections. The major risk factors for dissemination are race and immunosuppression. The most common sites of dissemination are the skin, lymph nodes, bone and meninges. Diagnosis is aided by investigation of the patient's clinical history, delayed-type hypersensitivity skin test reaction, serologic testing, and recovery of organisms from infected tissue or secretions for direct examination and culture. Fungicidal agents are not available, fortunately, fungistatic therapy allows many patients to recover. The availability of both intravenous/intrathecal and oral agents now allows more therapeutic flexibility in the treatment of this disease.

AB - Coccidioidomycosis is a largely self-limited fungal respiratory illness. However, the infrequent case of progressive or disseminated disease can be devastating. As international travel to and from endemic areas increases, physicians unfamiliar with the disease may be called upon to recognize and treat serious coccidioidal infections. The major risk factors for dissemination are race and immunosuppression. The most common sites of dissemination are the skin, lymph nodes, bone and meninges. Diagnosis is aided by investigation of the patient's clinical history, delayed-type hypersensitivity skin test reaction, serologic testing, and recovery of organisms from infected tissue or secretions for direct examination and culture. Fungicidal agents are not available, fortunately, fungistatic therapy allows many patients to recover. The availability of both intravenous/intrathecal and oral agents now allows more therapeutic flexibility in the treatment of this disease.

UR - http://www.scopus.com/inward/record.url?scp=0024475260&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024475260&partnerID=8YFLogxK

U2 - 10.1007/BF01964061

DO - 10.1007/BF01964061

M3 - Article

C2 - 2502411

AN - SCOPUS:0024475260

VL - 8

SP - 466

EP - 473

JO - European Journal of Clinical Microbiology and Infectious Diseases

JF - European Journal of Clinical Microbiology and Infectious Diseases

SN - 0934-9723

IS - 5

ER -