Coccidioidomycosis

Research output: Contribution to journalArticle

145 Citations (Scopus)

Abstract

Coccidioidomycosis is a systemic fungal infection endemic to the southwestern United States and other parts of the western hemisphere. Although producing a wide range of disorders in healthy persons, immunosuppression predisposes to especially severe disease. Thus, a knowledge of the pathogenesis of coccidioidal infections and its relation to the normal immune responses is useful to understand the diversity of problems that Coccidioides immitis may cause. Diagnosis usually requires laboratory studies such as fungal culture or specific serologic testing. Fortunately, many patients do not need to be treated for the infection to resolve. Therapy for the more severe forms of coccidioidal infection was once limited to amphotericin B but now includes azole antifungal agents. These expanded alternatives now require physicians to weigh many factors in determining the best management for specific patients.

Original languageEnglish (US)
Pages (from-to)153-171
Number of pages19
JournalWestern Journal of Medicine
Volume159
Issue number2
StatePublished - 1993
Externally publishedYes

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Coccidioidomycosis
Infection
Southwestern United States
Coccidioides
Azoles
Mycoses
Antifungal Agents
Amphotericin B
Immunosuppression
Physicians
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Coccidioidomycosis. / Galgiani, John N.

In: Western Journal of Medicine, Vol. 159, No. 2, 1993, p. 153-171.

Research output: Contribution to journalArticle

Galgiani, JN 1993, 'Coccidioidomycosis', Western Journal of Medicine, vol. 159, no. 2, pp. 153-171.
Galgiani, John N. / Coccidioidomycosis. In: Western Journal of Medicine. 1993 ; Vol. 159, No. 2. pp. 153-171.
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