Cognitive outcomes for extremely preterm/extremely low birth weight children in kindergarten

Leah J. Orchinik, H. Gerry Taylor, Kimberly Andrews Espy, Nori Minich, Nancy Klein, Tiffany Sheffield, Maureen Hack

Research output: Contribution to journalArticle

68 Scopus citations

Abstract

Our objectives were to examine cognitive outcomes for extremely preterm/extremely low birth weight (EPT/ELBW, gestational age <28 weeks and/or birth weight <1000 g) children in kindergarten and the associations of these outcomes with neonatal factors, early childhood neurodevelopmental impairment, and socioeconomic status (SES). The sample comprised a hospital-based 2001-2003 birth cohort of 148 EPT/ELBW children (mean birth weight 818 g; mean gestational age 26 weeks) and a comparison group of 111 term-born normal birth weight (NBW) classmate controls. Controlling for background factors, the EPT/ELBW group had pervasive deficits relative to the NBW group on a comprehensive test battery, with rates of cognitive deficits that were 3 to 6 times higher in the EPT/ELBW group. Deficits on a measure of response inhibition were found in 48% versus 10%, odds ratio (95% confidence interval) = 7.32 (3.32, 16.16), p <.001. Deficits on measures of executive function and motor and perceptual-motor abilities were found even when controlling for acquired verbal knowledge. Neonatal risk factors, early neurodevelopmental impairment, and lower SES were associated with higher rates of deficits within the EPT/ELBW group. The findings document both global and selective cognitive deficits in EPT/ELBW children at school entry and justify efforts at early identification and intervention.

Original languageEnglish (US)
Pages (from-to)1067-1079
Number of pages13
JournalJournal of the International Neuropsychological Society
Volume17
Issue number6
DOIs
StatePublished - Nov 1 2011

Keywords

  • Child
  • Cognition
  • Executive function
  • Neuropsychological tests
  • Premature birth
  • Risk factors

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Psychology
  • Clinical Neurology
  • Psychiatry and Mental health

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