To strengthen homeland security, there is a critical need for new tools that can facilitate real time collaboration among various law enforcement agencies. Through a field study, we find that law enforcement work is knowledge intensive and involves complex collaborative processes interrelating a large number of disparate units in a loosely defined virtual organization. To support knowledge intensive collaboration, we propose a new workflow centric framework to seamlessly integrate previously separate techniques from the fields of information retrieval and workflow management. Specifically, we develop a collaborative workflow management framework for interagency crime analysis. The key contribution of our research is that by integrating various state-of-the-art techniques innovatively, the proposed system can support real time collaboration processes in a virtual organization that evolves dynamically.