Comparative aspects of coccidioidomycosis in animals and humans

Research output: Chapter in Book/Report/Conference proceedingConference contribution

39 Scopus citations

Abstract

Coccidioides spp. appear capable of infecting all mammals and at least some reptiles. Development of disease as a result of infection is species-dependent. Dogs seem to have a susceptibility similar to that of humans, with subclinical infections, mild-to-severe primary pulmonary disease, and disseminated disease. Whereas central nervous system disease in humans is typically meningitis, brain disease in dogs and cats takes the form of granulomatous parenchymal masses. Osteomyelitis is the most common form of disseminated disease in the dog, while skin lesions predominate in the cat. Orally administered azole antifungal agents are the backbone of therapy in animals as they are in humans.

Original languageEnglish (US)
Title of host publicationCoccidioidomycosis Sixth International Symposium
PublisherBlackwell Publishing Inc.
Pages395-403
Number of pages9
ISBN (Print)1573316881, 9781573316880
DOIs
StatePublished - Sep 2007

Publication series

NameAnnals of the New York Academy of Sciences
Volume1111
ISSN (Print)0077-8923
ISSN (Electronic)1749-6632

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Keywords

  • Cats
  • Coccidioides
  • Coccidioidomycosis
  • Dogs
  • Horses
  • Llamas
  • Primates

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

Cite this

Shubitz, L. F. (2007). Comparative aspects of coccidioidomycosis in animals and humans. In Coccidioidomycosis Sixth International Symposium (pp. 395-403). (Annals of the New York Academy of Sciences; Vol. 1111). Blackwell Publishing Inc.. https://doi.org/10.1196/annals.1406.007