Comparison of anterior chamber depth of normal and keratoconus eyes using scheimpflug photography

Charles R. Edmonds, Shu-Fen Wung, Bart Pemberton, Steven Surrett

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

OBJECTIVES: To compare the corneal anterior chamber depth (ACD) adjusted by age and sex in normal and keratoconus eyes. METHODS: Scheimpflug photography with the Oculus Pentacam was used to measure the ACD of 162 normal and 41 keratoconus patients. RESULTS: Univariate analysis showed that the mean ACD of 162 normal subjects (3.18 ± 0.32 mm) was borderline significantly less than in 41 keratoconus patients (3.28 ± 0.40 mm; P=0.079). However, we found that sex (P=0.001) and age (P<0.001) are significantly related to ACD in all patients. Women with normal eyes had a significantly lower mean ACD (3.13 ± 0.34 mm) than men (3.27 ± 0.28 mm, P=0.008). Women with keratoconus eyes also had a lower mean ACD (3.16 ± 0.39 mm) than men with keratoconus (3.42 ± 0.36 mm, P=0.032). Bivariate regression showed that with each additional year of aging, the ACD was decreased by an average of 0.012 mm in a normal eye (P<0.001) and by 0.014 mm in a keratoconus eye (P<0.001). Regression analysis showed that sex (P=0.003), age (P<0.001), and keratoconus (P=0.003) are all significant variables for determining ACD. After adjusting for age and sex, keratoconus eyes had a significantly higher mean ACD (3.34 ± 0.34 mm) than normal eyes (3.18 ± 0.28 mm) (P=0.003). CONCLUSIONS: Sex, age, and keratoconus are all significant variables for ACD. After adjusting for age, keratoconus eyes of both genders had a significantly higher ACD than normal eyes of both genders. Women showed lower mean ACD than men in both normal and keratoconus eyes.

Original languageEnglish (US)
Pages (from-to)120-122
Number of pages3
JournalEye and Contact Lens
Volume35
Issue number3
DOIs
StatePublished - May 2009

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Keratoconus
Photography
Anterior Chamber

Keywords

  • Anterior chamber depth
  • Keratoconus
  • Pentacam
  • Scheimpflug photography

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Comparison of anterior chamber depth of normal and keratoconus eyes using scheimpflug photography. / Edmonds, Charles R.; Wung, Shu-Fen; Pemberton, Bart; Surrett, Steven.

In: Eye and Contact Lens, Vol. 35, No. 3, 05.2009, p. 120-122.

Research output: Contribution to journalArticle

Edmonds, Charles R. ; Wung, Shu-Fen ; Pemberton, Bart ; Surrett, Steven. / Comparison of anterior chamber depth of normal and keratoconus eyes using scheimpflug photography. In: Eye and Contact Lens. 2009 ; Vol. 35, No. 3. pp. 120-122.
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abstract = "OBJECTIVES: To compare the corneal anterior chamber depth (ACD) adjusted by age and sex in normal and keratoconus eyes. METHODS: Scheimpflug photography with the Oculus Pentacam was used to measure the ACD of 162 normal and 41 keratoconus patients. RESULTS: Univariate analysis showed that the mean ACD of 162 normal subjects (3.18 ± 0.32 mm) was borderline significantly less than in 41 keratoconus patients (3.28 ± 0.40 mm; P=0.079). However, we found that sex (P=0.001) and age (P<0.001) are significantly related to ACD in all patients. Women with normal eyes had a significantly lower mean ACD (3.13 ± 0.34 mm) than men (3.27 ± 0.28 mm, P=0.008). Women with keratoconus eyes also had a lower mean ACD (3.16 ± 0.39 mm) than men with keratoconus (3.42 ± 0.36 mm, P=0.032). Bivariate regression showed that with each additional year of aging, the ACD was decreased by an average of 0.012 mm in a normal eye (P<0.001) and by 0.014 mm in a keratoconus eye (P<0.001). Regression analysis showed that sex (P=0.003), age (P<0.001), and keratoconus (P=0.003) are all significant variables for determining ACD. After adjusting for age and sex, keratoconus eyes had a significantly higher mean ACD (3.34 ± 0.34 mm) than normal eyes (3.18 ± 0.28 mm) (P=0.003). CONCLUSIONS: Sex, age, and keratoconus are all significant variables for ACD. After adjusting for age, keratoconus eyes of both genders had a significantly higher ACD than normal eyes of both genders. Women showed lower mean ACD than men in both normal and keratoconus eyes.",
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AU - Edmonds, Charles R.

AU - Wung, Shu-Fen

AU - Pemberton, Bart

AU - Surrett, Steven

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N2 - OBJECTIVES: To compare the corneal anterior chamber depth (ACD) adjusted by age and sex in normal and keratoconus eyes. METHODS: Scheimpflug photography with the Oculus Pentacam was used to measure the ACD of 162 normal and 41 keratoconus patients. RESULTS: Univariate analysis showed that the mean ACD of 162 normal subjects (3.18 ± 0.32 mm) was borderline significantly less than in 41 keratoconus patients (3.28 ± 0.40 mm; P=0.079). However, we found that sex (P=0.001) and age (P<0.001) are significantly related to ACD in all patients. Women with normal eyes had a significantly lower mean ACD (3.13 ± 0.34 mm) than men (3.27 ± 0.28 mm, P=0.008). Women with keratoconus eyes also had a lower mean ACD (3.16 ± 0.39 mm) than men with keratoconus (3.42 ± 0.36 mm, P=0.032). Bivariate regression showed that with each additional year of aging, the ACD was decreased by an average of 0.012 mm in a normal eye (P<0.001) and by 0.014 mm in a keratoconus eye (P<0.001). Regression analysis showed that sex (P=0.003), age (P<0.001), and keratoconus (P=0.003) are all significant variables for determining ACD. After adjusting for age and sex, keratoconus eyes had a significantly higher mean ACD (3.34 ± 0.34 mm) than normal eyes (3.18 ± 0.28 mm) (P=0.003). CONCLUSIONS: Sex, age, and keratoconus are all significant variables for ACD. After adjusting for age, keratoconus eyes of both genders had a significantly higher ACD than normal eyes of both genders. Women showed lower mean ACD than men in both normal and keratoconus eyes.

AB - OBJECTIVES: To compare the corneal anterior chamber depth (ACD) adjusted by age and sex in normal and keratoconus eyes. METHODS: Scheimpflug photography with the Oculus Pentacam was used to measure the ACD of 162 normal and 41 keratoconus patients. RESULTS: Univariate analysis showed that the mean ACD of 162 normal subjects (3.18 ± 0.32 mm) was borderline significantly less than in 41 keratoconus patients (3.28 ± 0.40 mm; P=0.079). However, we found that sex (P=0.001) and age (P<0.001) are significantly related to ACD in all patients. Women with normal eyes had a significantly lower mean ACD (3.13 ± 0.34 mm) than men (3.27 ± 0.28 mm, P=0.008). Women with keratoconus eyes also had a lower mean ACD (3.16 ± 0.39 mm) than men with keratoconus (3.42 ± 0.36 mm, P=0.032). Bivariate regression showed that with each additional year of aging, the ACD was decreased by an average of 0.012 mm in a normal eye (P<0.001) and by 0.014 mm in a keratoconus eye (P<0.001). Regression analysis showed that sex (P=0.003), age (P<0.001), and keratoconus (P=0.003) are all significant variables for determining ACD. After adjusting for age and sex, keratoconus eyes had a significantly higher mean ACD (3.34 ± 0.34 mm) than normal eyes (3.18 ± 0.28 mm) (P=0.003). CONCLUSIONS: Sex, age, and keratoconus are all significant variables for ACD. After adjusting for age, keratoconus eyes of both genders had a significantly higher ACD than normal eyes of both genders. Women showed lower mean ACD than men in both normal and keratoconus eyes.

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