Comparison of MR and PET imaging for the evaluation of liver metastases

Ming Yang, Diego R. Martin, Nevzat Karabulut, Mathis P. Frick

Research output: Contribution to journalArticle

49 Scopus citations

Abstract

Purpose: To compare the accuracy of fluoro-18-deoxyglucose positron emission tomography (FDG-PET) and dynamic-enhanced magnetic resonance imaging (MRI) scans in the diagnosis of liver metastatic lesions from colon and other sources. Materials and Methods: Thirty consecutive patients with known or suspected metastatic lesions were scanned by both MRI and PET. Histopathology and/or clinical outcome, including cross-sectional imaging follow up, were used as a gold standard. Results: Of 30 patients, 16 were positive by pathology and/or clinical outcome and 14 were negative for liver metastases. The sensitivity, specificity, and positive and negative predictive values on MRI were 85.7%, 100%, 100%, and 89%, respectively, compared to 71%, 93.7%, 90.9%, and 79% on FDG-PET. The difference between the two methods was not significant (X2 = 0.2, P > 0.05). Conclusion: Our study showed no significant difference in detection of liver metastases using MRI or FDG-PET. However, MRI has advantages in spatial resolution and lesion characterization.

Original languageEnglish (US)
Pages (from-to)343-349
Number of pages7
JournalJournal of Magnetic Resonance Imaging
Volume17
Issue number3
DOIs
StatePublished - Mar 1 2003
Externally publishedYes

Keywords

  • FDG-PET
  • Liver lesions
  • MRI
  • Malignancy
  • Metastatic

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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