Comparison of the different characteristics of sensed reflux events among different heartburn groups.

Ron Schey, Michael Shapiro, Tomas Navarro-Rodriguez, Shira S. Fass, Bing Han, Christopher S Wendel, Ronnie Fass

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5 Scopus citations

Abstract

Presently, there are no studies comparing sensed acid reflux event (SARE) characteristics among different heartburn groups. Our aim was to compare the different esophageal acid reflux characteristics of an SARE among the different heartburn groups. Patients with heartburn underwent endoscopy and pH testing and were stratified into 3 groups: erosive esophagitis (EE), nonerosive reflux disease (NERD), and functional heartburn (FH). Patients underwent esophageal pH testing using a 4-sensor pH probe, with the most distal pH sensor positioned 1 cm> lower esophageal sphincter (LES). Twenty-two patients had EE, 15 NERD, and 13 FH (M/F: 20/2, 12/3, 5/8, mean age: 51.5+/-3.7, 50.1+/-4.2, 50.3+/-3.8, respectively). The percentage of SAREs at 1 cm>LES that had reached 16 cm>LES was significantly higher in the FH group compared with NERD and EE (P<0.05). EE demonstrated the lowest nadir during an SARE and NERD the most acid reflux events before an SARE (up to 4 h). Patients with FH demonstrated the most SAREs that reached the proximal esophagus. EE patients demonstrated the lowest nadir pH during an SARE and NERD patients the most acid reflux events before an SARE, as compared with the other heartburn groups.

Original languageEnglish (US)
Pages (from-to)699-704
Number of pages6
JournalJournal of Clinical Gastroenterology
Volume43
Issue number8
Publication statusPublished - Sep 2009
Externally publishedYes

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ASJC Scopus subject areas

  • Gastroenterology

Cite this

Schey, R., Shapiro, M., Navarro-Rodriguez, T., Fass, S. S., Han, B., Wendel, C. S., & Fass, R. (2009). Comparison of the different characteristics of sensed reflux events among different heartburn groups. Journal of Clinical Gastroenterology, 43(8), 699-704.