Comparison of titanium vascular closure staples with suture repair of the thoracic aorta in swine

S. Deb, B. Martin, L. Sun, D. Burris, D. Wherry, E. Pikoulis, Peter M Rhee

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Objective: Devices that reduce technical difficulty and anastigmatic time when repairing large vessels such as the thoracic aorta would be beneficial. The aim of this study was to determine if titanium vascular closure staples (3 mm) could be safely and quickly applied in the repair of large vessels such as the thoracic aorta. Design: Through a left thoracotomy in 10 female swine (110 to 130 lb), an interposition graft (14 to 16 mm textile) was placed into the aorta distal to the left subclavian artery. Animals were randomized at the time of repair to either running sutures (n = 5; 6-0 polypropylene) or vascular closure staples (n = 5; 3 mm). The anastomosis was evaluated after 2 months with aortograms, and the aorta was harvested to evaluate healing. Results: The clamp times (mean ± SD) were 30.8 ± 8.2 min for suture repair and 24.8 ± 5.1 min for vascular closure staple repair (p = 0.2). Anastomosis times were 20.0 ± 6.2 min for the suture group and 16.4 ± 6.4 min for the vascular closure staple group (p = 0.4). Arch aortograms at 2 months revealed no significant difference in luminal narrowing between the two groups. Gross and microscopic examination revealed no thrombosis, well-healed wounds with a continuous intimal layer, and no differences in intimal thickness or inflammation between the two groups. Conclusion: Vascular closure staples were equivalent to sutures in terms of durability, graft patency, and wound healing at 2 months. Vascular closure staples may offer the trauma surgeon a quick and easy alternative when repairing large vessels such as the thoracic aorta.

Original languageEnglish (US)
Pages (from-to)1762-1768
Number of pages7
JournalChest
Volume118
Issue number6
DOIs
StatePublished - 2000
Externally publishedYes

Fingerprint

Titanium
Thoracic Aorta
Sutures
Blood Vessels
Swine
Tunica Intima
Aorta
Transplants
Subclavian Artery
Textiles
Polypropylenes
Wounds and Injuries
Thoracotomy
Wound Healing
Thrombosis
Inflammation
Equipment and Supplies

Keywords

  • Anastomosis
  • Aorta
  • Graft
  • Healing
  • Suture
  • Swine
  • Thorax
  • Thrombosis
  • Trauma
  • Vascula r closure staples

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Comparison of titanium vascular closure staples with suture repair of the thoracic aorta in swine. / Deb, S.; Martin, B.; Sun, L.; Burris, D.; Wherry, D.; Pikoulis, E.; Rhee, Peter M.

In: Chest, Vol. 118, No. 6, 2000, p. 1762-1768.

Research output: Contribution to journalArticle

Deb, S, Martin, B, Sun, L, Burris, D, Wherry, D, Pikoulis, E & Rhee, PM 2000, 'Comparison of titanium vascular closure staples with suture repair of the thoracic aorta in swine', Chest, vol. 118, no. 6, pp. 1762-1768. https://doi.org/10.1378/chest.118.6.1762
Deb, S. ; Martin, B. ; Sun, L. ; Burris, D. ; Wherry, D. ; Pikoulis, E. ; Rhee, Peter M. / Comparison of titanium vascular closure staples with suture repair of the thoracic aorta in swine. In: Chest. 2000 ; Vol. 118, No. 6. pp. 1762-1768.
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AU - Pikoulis, E.

AU - Rhee, Peter M

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N2 - Objective: Devices that reduce technical difficulty and anastigmatic time when repairing large vessels such as the thoracic aorta would be beneficial. The aim of this study was to determine if titanium vascular closure staples (3 mm) could be safely and quickly applied in the repair of large vessels such as the thoracic aorta. Design: Through a left thoracotomy in 10 female swine (110 to 130 lb), an interposition graft (14 to 16 mm textile) was placed into the aorta distal to the left subclavian artery. Animals were randomized at the time of repair to either running sutures (n = 5; 6-0 polypropylene) or vascular closure staples (n = 5; 3 mm). The anastomosis was evaluated after 2 months with aortograms, and the aorta was harvested to evaluate healing. Results: The clamp times (mean ± SD) were 30.8 ± 8.2 min for suture repair and 24.8 ± 5.1 min for vascular closure staple repair (p = 0.2). Anastomosis times were 20.0 ± 6.2 min for the suture group and 16.4 ± 6.4 min for the vascular closure staple group (p = 0.4). Arch aortograms at 2 months revealed no significant difference in luminal narrowing between the two groups. Gross and microscopic examination revealed no thrombosis, well-healed wounds with a continuous intimal layer, and no differences in intimal thickness or inflammation between the two groups. Conclusion: Vascular closure staples were equivalent to sutures in terms of durability, graft patency, and wound healing at 2 months. Vascular closure staples may offer the trauma surgeon a quick and easy alternative when repairing large vessels such as the thoracic aorta.

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