Consciousness in the universe: A review of the 'Orch OR' theory

Stuart R Hameroff, Roger Penrose

Research output: Contribution to journalArticle

238 Citations (Scopus)

Abstract

The nature of consciousness, the mechanism by which it occurs in the brain, and its ultimate place in the universe are unknown. We proposed in the mid 1990's that consciousness depends on biologically 'orchestrated' coherent quantum processes in collections of microtubules within brain neurons, that these quantum processes correlate with, and regulate, neuronal synaptic and membrane activity, and that the continuous Schrödinger evolution of each such process terminates in accordance with the specific Diósi-Penrose (DP) scheme of 'objective reduction' ('OR') of the quantum state. This orchestrated OR activity ('Orch OR') is taken to result in moments of conscious awareness and/or choice. The DP form of OR is related to the fundamentals of quantum mechanics and space-time geometry, so Orch OR suggests that there is a connection between the brain's biomolecular processes and the basic structure of the universe. Here we review Orch OR in light of criticisms and developments in quantum biology, neuroscience, physics and cosmology. We also introduce a novel suggestion of 'beat frequencies' of faster microtubule vibrations as a possible source of the observed electro-encephalographic ('EEG') correlates of consciousness. We conclude that consciousness plays an intrinsic role in the universe.

Original languageEnglish (US)
Pages (from-to)39-78
Number of pages40
JournalPhysics of Life Reviews
Volume11
Issue number1
DOIs
StatePublished - Mar 2014

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consciousness
Consciousness
Brain
universe
brain
Microtubules
Cosmology
microtubules
Quantum theory
neurology
Synaptic Membranes
beat frequencies
neurophysiology
Neurons
Physics
physics
Neurosciences
Vibration
Mechanics
neurons

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Physics and Astronomy(all)
  • Artificial Intelligence

Cite this

Consciousness in the universe : A review of the 'Orch OR' theory. / Hameroff, Stuart R; Penrose, Roger.

In: Physics of Life Reviews, Vol. 11, No. 1, 03.2014, p. 39-78.

Research output: Contribution to journalArticle

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