Continuous noninvasive hemoglobin monitor from pulse Ox: Ready for prime time?

Bellal A Joseph, Pantelis Hadjizacharia, Hassan Aziz, Kara Snyder, Julie Wynne, Narong Kulvatunyou, Andrew - Tang, Terence S Okeeffe, Rifat - Latifi, Randall S Friese, Peter M Rhee

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Background: Advances in technology have allowed for continuous noninvasive hemoglobin monitoring (SpHb), which may enable earlier detection of hemorrhage and more efficient surgical and/or blood transfusion management. The use of SpHb has not been described in the trauma population. The purpose of the present study was to evaluate the accuracy of a SpHb measurement device in severely injured trauma patients. Methods: We performed a prospective cohort analysis of severely injured trauma patients admitted to the intensive care unit (ICU) at our level I trauma center over a 6 month period. Serial IHb (invasive hemoglobin) levels and SpHb for the first 72 h were measured. Each SpHb measurement was matched with a corresponding IHb measurement. We defined normal Hgb as >8 mg/dL and low Hgb as <8 mg/dL. Data were then grouped based on Hgb level. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, and Spearman correlation coefficient plot were calculated. Results: A total of 23 trauma patients with 89 data pairs were reviewed. Eighty-six percent of the patients were male with a mean age of 32 years and a mean injury severity score (ISS) of 21.1 ± 14. Invasive hemoglobin had a range of 7.2-16.9 and SpHb had a range of 3.3-15.2. The average mean and difference between IHb and SpHb were 10.7 and 1, respectively. Continuous noninvasive hemoglobin measurement did not record data points 13.5 % of the time. The Spearman correlation plot revealed a correlation of R = 0.670 (p < 0.001). After dichotomization with Hgb > 8, SpHb was found to have a sensitivity of 91 %, PPV 96 %, specificity 40 %, NPV 20 %, and an accuracy of 88 %. Conclusions: The continuous noninvasive hemoglobin monitor does not appear to represent serum hemoglobin levels accurately in severely injured trauma patients. However, we were able to identify utility for this noninvasive tool when Hgb was dichotomized into normal or low levels.

Original languageEnglish (US)
Pages (from-to)525-529
Number of pages5
JournalWorld Journal of Surgery
Volume37
Issue number3
DOIs
StatePublished - Mar 2013

Fingerprint

Hemoglobins
Wounds and Injuries
Trauma Centers
Blood Transfusion
Intensive Care Units
Cohort Studies
Hemorrhage
Technology
Equipment and Supplies
Serum
Population

ASJC Scopus subject areas

  • Surgery

Cite this

Continuous noninvasive hemoglobin monitor from pulse Ox : Ready for prime time? / Joseph, Bellal A; Hadjizacharia, Pantelis; Aziz, Hassan; Snyder, Kara; Wynne, Julie; Kulvatunyou, Narong; Tang, Andrew -; Okeeffe, Terence S; Latifi, Rifat -; Friese, Randall S; Rhee, Peter M.

In: World Journal of Surgery, Vol. 37, No. 3, 03.2013, p. 525-529.

Research output: Contribution to journalArticle

@article{f631525ca08144cd9afbbdad224121a5,
title = "Continuous noninvasive hemoglobin monitor from pulse Ox: Ready for prime time?",
abstract = "Background: Advances in technology have allowed for continuous noninvasive hemoglobin monitoring (SpHb), which may enable earlier detection of hemorrhage and more efficient surgical and/or blood transfusion management. The use of SpHb has not been described in the trauma population. The purpose of the present study was to evaluate the accuracy of a SpHb measurement device in severely injured trauma patients. Methods: We performed a prospective cohort analysis of severely injured trauma patients admitted to the intensive care unit (ICU) at our level I trauma center over a 6 month period. Serial IHb (invasive hemoglobin) levels and SpHb for the first 72 h were measured. Each SpHb measurement was matched with a corresponding IHb measurement. We defined normal Hgb as >8 mg/dL and low Hgb as <8 mg/dL. Data were then grouped based on Hgb level. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, and Spearman correlation coefficient plot were calculated. Results: A total of 23 trauma patients with 89 data pairs were reviewed. Eighty-six percent of the patients were male with a mean age of 32 years and a mean injury severity score (ISS) of 21.1 ± 14. Invasive hemoglobin had a range of 7.2-16.9 and SpHb had a range of 3.3-15.2. The average mean and difference between IHb and SpHb were 10.7 and 1, respectively. Continuous noninvasive hemoglobin measurement did not record data points 13.5 {\%} of the time. The Spearman correlation plot revealed a correlation of R = 0.670 (p < 0.001). After dichotomization with Hgb > 8, SpHb was found to have a sensitivity of 91 {\%}, PPV 96 {\%}, specificity 40 {\%}, NPV 20 {\%}, and an accuracy of 88 {\%}. Conclusions: The continuous noninvasive hemoglobin monitor does not appear to represent serum hemoglobin levels accurately in severely injured trauma patients. However, we were able to identify utility for this noninvasive tool when Hgb was dichotomized into normal or low levels.",
author = "Joseph, {Bellal A} and Pantelis Hadjizacharia and Hassan Aziz and Kara Snyder and Julie Wynne and Narong Kulvatunyou and Tang, {Andrew -} and Okeeffe, {Terence S} and Latifi, {Rifat -} and Friese, {Randall S} and Rhee, {Peter M}",
year = "2013",
month = "3",
doi = "10.1007/s00268-012-1871-y",
language = "English (US)",
volume = "37",
pages = "525--529",
journal = "World Journal of Surgery",
issn = "0364-2313",
publisher = "Springer New York",
number = "3",

}

TY - JOUR

T1 - Continuous noninvasive hemoglobin monitor from pulse Ox

T2 - Ready for prime time?

AU - Joseph, Bellal A

AU - Hadjizacharia, Pantelis

AU - Aziz, Hassan

AU - Snyder, Kara

AU - Wynne, Julie

AU - Kulvatunyou, Narong

AU - Tang, Andrew -

AU - Okeeffe, Terence S

AU - Latifi, Rifat -

AU - Friese, Randall S

AU - Rhee, Peter M

PY - 2013/3

Y1 - 2013/3

N2 - Background: Advances in technology have allowed for continuous noninvasive hemoglobin monitoring (SpHb), which may enable earlier detection of hemorrhage and more efficient surgical and/or blood transfusion management. The use of SpHb has not been described in the trauma population. The purpose of the present study was to evaluate the accuracy of a SpHb measurement device in severely injured trauma patients. Methods: We performed a prospective cohort analysis of severely injured trauma patients admitted to the intensive care unit (ICU) at our level I trauma center over a 6 month period. Serial IHb (invasive hemoglobin) levels and SpHb for the first 72 h were measured. Each SpHb measurement was matched with a corresponding IHb measurement. We defined normal Hgb as >8 mg/dL and low Hgb as <8 mg/dL. Data were then grouped based on Hgb level. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, and Spearman correlation coefficient plot were calculated. Results: A total of 23 trauma patients with 89 data pairs were reviewed. Eighty-six percent of the patients were male with a mean age of 32 years and a mean injury severity score (ISS) of 21.1 ± 14. Invasive hemoglobin had a range of 7.2-16.9 and SpHb had a range of 3.3-15.2. The average mean and difference between IHb and SpHb were 10.7 and 1, respectively. Continuous noninvasive hemoglobin measurement did not record data points 13.5 % of the time. The Spearman correlation plot revealed a correlation of R = 0.670 (p < 0.001). After dichotomization with Hgb > 8, SpHb was found to have a sensitivity of 91 %, PPV 96 %, specificity 40 %, NPV 20 %, and an accuracy of 88 %. Conclusions: The continuous noninvasive hemoglobin monitor does not appear to represent serum hemoglobin levels accurately in severely injured trauma patients. However, we were able to identify utility for this noninvasive tool when Hgb was dichotomized into normal or low levels.

AB - Background: Advances in technology have allowed for continuous noninvasive hemoglobin monitoring (SpHb), which may enable earlier detection of hemorrhage and more efficient surgical and/or blood transfusion management. The use of SpHb has not been described in the trauma population. The purpose of the present study was to evaluate the accuracy of a SpHb measurement device in severely injured trauma patients. Methods: We performed a prospective cohort analysis of severely injured trauma patients admitted to the intensive care unit (ICU) at our level I trauma center over a 6 month period. Serial IHb (invasive hemoglobin) levels and SpHb for the first 72 h were measured. Each SpHb measurement was matched with a corresponding IHb measurement. We defined normal Hgb as >8 mg/dL and low Hgb as <8 mg/dL. Data were then grouped based on Hgb level. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, and Spearman correlation coefficient plot were calculated. Results: A total of 23 trauma patients with 89 data pairs were reviewed. Eighty-six percent of the patients were male with a mean age of 32 years and a mean injury severity score (ISS) of 21.1 ± 14. Invasive hemoglobin had a range of 7.2-16.9 and SpHb had a range of 3.3-15.2. The average mean and difference between IHb and SpHb were 10.7 and 1, respectively. Continuous noninvasive hemoglobin measurement did not record data points 13.5 % of the time. The Spearman correlation plot revealed a correlation of R = 0.670 (p < 0.001). After dichotomization with Hgb > 8, SpHb was found to have a sensitivity of 91 %, PPV 96 %, specificity 40 %, NPV 20 %, and an accuracy of 88 %. Conclusions: The continuous noninvasive hemoglobin monitor does not appear to represent serum hemoglobin levels accurately in severely injured trauma patients. However, we were able to identify utility for this noninvasive tool when Hgb was dichotomized into normal or low levels.

UR - http://www.scopus.com/inward/record.url?scp=84874118235&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84874118235&partnerID=8YFLogxK

U2 - 10.1007/s00268-012-1871-y

DO - 10.1007/s00268-012-1871-y

M3 - Article

C2 - 23196342

AN - SCOPUS:84874118235

VL - 37

SP - 525

EP - 529

JO - World Journal of Surgery

JF - World Journal of Surgery

SN - 0364-2313

IS - 3

ER -