Convergent synthesis of geometrically disassembling dendrimers using Cu(I)-catalyzed C-O bond formation

Nathan W. Polaske, Michael L. Szalai, Charles S. Shanahan, Dominic V Mcgrath

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The convergent synthesis of geometrically degradable dendrimers based on the 2,4-bis(hydroxymethyl)phenol subunit is presented. The key step of the synthetic scheme involves the CuI/3,4,7,8-tetramethyl-1,10-phenanthroline- catalyzed coupling of aryl iodides and alcohols. The synthesis and disassembly of these compounds is discussed.

Original languageEnglish (US)
Pages (from-to)4944-4947
Number of pages4
JournalOrganic Letters
Volume12
Issue number21
DOIs
StatePublished - Nov 5 2010

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Dendrimers
dendrimers
Iodides
Alcohols
synthesis
Phenol
phenols
iodides
alcohols
4-hydroxybenzyl alcohol
3,4,7,8-tetramethyl-1,10-phenanthroline

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Convergent synthesis of geometrically disassembling dendrimers using Cu(I)-catalyzed C-O bond formation. / Polaske, Nathan W.; Szalai, Michael L.; Shanahan, Charles S.; Mcgrath, Dominic V.

In: Organic Letters, Vol. 12, No. 21, 05.11.2010, p. 4944-4947.

Research output: Contribution to journalArticle

Polaske, Nathan W. ; Szalai, Michael L. ; Shanahan, Charles S. ; Mcgrath, Dominic V. / Convergent synthesis of geometrically disassembling dendrimers using Cu(I)-catalyzed C-O bond formation. In: Organic Letters. 2010 ; Vol. 12, No. 21. pp. 4944-4947.
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