Cord blood stem cells and regenerative medicine

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Umbilical cord blood (CB) can provide a virtually unlimited source of diverse stem cells that can be used for hematologic transplants as well as in a variety of regenerative medicine applications. Cord blood units can be frozen and preserved in liquid nitrogen dewars for prolonged periods of time, having been frozen in time at the peak of their biological activity. Multipotent stem cells are available in large numbers in both umbilical cord blood (CB) and cord tissue (CT). CB stem cells are capable of giving rise to hematopoietic, epithelial, endothelial, and neural tissues both in vitro and in vivo. CT stem cells are capable of giving rise to various mesenchymal lineages, including bone, cartilage, and fat. Thus, CB and CT stem cells are candidates to develop stem-cell-based therapies for a wide variety of diseases, including cardiovascular, ophthalmic, orthopedic, neurological, and endocrine diseases. CB and CT have now been used in several regenerative medicine clinical studies, examples of which include cerebral palsy and non-healing bone fractures. CB and CT represent an invaluable source of stem cells that have both immediate and future applications for the individual donor.

Original languageEnglish (US)
Title of host publicationRegenerative Medicine and Cell Therapy
PublisherHumana Press Inc.
Pages301-312
Number of pages12
ISBN (Electronic)9781627030977
ISBN (Print)9781627030984
DOIs
StatePublished - Jan 1 2013

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Regenerative Medicine
Stem cells
Fetal Blood
Blood Cells
Blood
Stem Cells
Tissue
Multipotent Stem Cells
Endocrine System Diseases
Bone Fractures
Cerebral Palsy
Cell- and Tissue-Based Therapy
Bone
Cartilage
Endothelium
Orthopedics
Cardiovascular Diseases
Nitrogen
Dewars
Fats

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Harris, D. T. (2013). Cord blood stem cells and regenerative medicine. In Regenerative Medicine and Cell Therapy (pp. 301-312). Humana Press Inc.. https://doi.org/10.1007/978-1-62703-098-4_14

Cord blood stem cells and regenerative medicine. / Harris, David T.

Regenerative Medicine and Cell Therapy. Humana Press Inc., 2013. p. 301-312.

Research output: Chapter in Book/Report/Conference proceedingChapter

Harris, DT 2013, Cord blood stem cells and regenerative medicine. in Regenerative Medicine and Cell Therapy. Humana Press Inc., pp. 301-312. https://doi.org/10.1007/978-1-62703-098-4_14
Harris DT. Cord blood stem cells and regenerative medicine. In Regenerative Medicine and Cell Therapy. Humana Press Inc. 2013. p. 301-312 https://doi.org/10.1007/978-1-62703-098-4_14
Harris, David T. / Cord blood stem cells and regenerative medicine. Regenerative Medicine and Cell Therapy. Humana Press Inc., 2013. pp. 301-312
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