TY - JOUR
T1 - Corneal elevation in a large number of myopic Chinese patients
AU - Ying, Jinglu
AU - Wang, Qinmei
AU - Belin, Michael W
AU - Wan, Ting
AU - Lin, Shishi
AU - Feng, Yifan
AU - Gao, Rongrong
AU - Huang, Jinhai
PY - 2015/3/7
Y1 - 2015/3/7
N2 - Purpose: To establish a normative database for corneal elevation in Chinese myopic patients who underwent refractive surgery, and analyze the association of corneal elevation with sex, age, and ocular parameters. Methods: A total of 3000 eyes in 1500 patients were evaluated with the Pentacam. Anterior and posterior elevations were measured at the apex and thinnest point. Normative thresholds were defined according to the Tukey method. Univariate and multivariate analyses were performed to assess the association of corneal elevation with sex, age, and ocular parameters. Results: Normal upper limits for corneal elevation in adult Chinese were 4.95. μm, 5.25. μm, 6.2. μm, and 11.0. μm at the anterior apex, anterior thinnest point, posterior apex, and posterior thinnest point, respectively. Thinner corneal pachymetry at the apex and greater anterior corneal astigmatism tended to show greater anterior corneal elevation values. Younger age, greater anterior corneal astigmatism, lower anterior and posterior keratometry, and shallower anterior chamber depth resulted in greater posterior corneal elevation values. Conclusions: Locally derived thresholds may offer higher sensitivity and specificity when screening eyes for myopic refractive surgery, and keratoconic and post-orthokeratology eyes. Anterior and posterior corneal elevation at the apex and thinnest point were associated significantly with anterior corneal astigmatism, showing a positive correlation.
AB - Purpose: To establish a normative database for corneal elevation in Chinese myopic patients who underwent refractive surgery, and analyze the association of corneal elevation with sex, age, and ocular parameters. Methods: A total of 3000 eyes in 1500 patients were evaluated with the Pentacam. Anterior and posterior elevations were measured at the apex and thinnest point. Normative thresholds were defined according to the Tukey method. Univariate and multivariate analyses were performed to assess the association of corneal elevation with sex, age, and ocular parameters. Results: Normal upper limits for corneal elevation in adult Chinese were 4.95. μm, 5.25. μm, 6.2. μm, and 11.0. μm at the anterior apex, anterior thinnest point, posterior apex, and posterior thinnest point, respectively. Thinner corneal pachymetry at the apex and greater anterior corneal astigmatism tended to show greater anterior corneal elevation values. Younger age, greater anterior corneal astigmatism, lower anterior and posterior keratometry, and shallower anterior chamber depth resulted in greater posterior corneal elevation values. Conclusions: Locally derived thresholds may offer higher sensitivity and specificity when screening eyes for myopic refractive surgery, and keratoconic and post-orthokeratology eyes. Anterior and posterior corneal elevation at the apex and thinnest point were associated significantly with anterior corneal astigmatism, showing a positive correlation.
KW - Corneal elevation
KW - Myopia
KW - Normative database
KW - Scheimpflug imaging
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U2 - 10.1016/j.clae.2016.01.005
DO - 10.1016/j.clae.2016.01.005
M3 - Article
C2 - 26851137
AN - SCOPUS:84956598757
JO - Contact Lens and Anterior Eye
JF - Contact Lens and Anterior Eye
SN - 1367-0484
ER -