Coronary artery bypass grafting with cardiopulmonary bypass versus off-pump cardiopulmonary bypass grafting: Does eliminating the pump reduce morbidity and cost?

David A. Bull, Leigh A. Neumayer, James C. Stringham, Patricia Meldrum, David G. Affleck, Shreekanth V. Karwande

Research output: Contribution to journalArticle

87 Scopus citations

Abstract

Background. Cardiopulmonary bypass (CPB) may contribute to the complications and cost of coronary artery bypass grafting (CABG). Off-pump CABG (OPCAB) allows coronary revascularization without CPB. We hypothesized that OPCAB provides satisfactory graft patency while reducing complications and cost compared with CABG with CPB. Methods. We prospectively followed 80 patients undergoing CABG: 40 patients undergoing OPCAB and 40 patients undergoing CABG with CPB. OPCAB patients underwent angiography within 48 hours of surgery to determine early graft patency. Incidence of complications, length of stay, and costs were recorded for each patient. The influence of the number of vessels bypassed was analyzed. Results. OPCAB patients (n = 40) underwent grafting of 2.7 ± 0.7 vessels per patient compared with 3.6 ± 0.8 vessels per patient in the CABG with CPB group (n = 40) (p < 0.0001). Angiography demonstrated 105 of 108 (97%) of grafts were patent in the OPCAB group. Incidence of complications, length of stay, and costs did not differ between the OPCAB and CABG with CPB groups. Number of vessels grafted showed a positive correlation to total costs in both groups. Conclusions. While OPCAB provided satisfactory early graft patency, there was no significant difference between OPCAB and CABG with CPB with regard to cost, length of stay, or incidence of complications. In this study, eliminating CPB did not reduce morbidity or cost after CABG.

Original languageEnglish (US)
Pages (from-to)170-175
Number of pages6
JournalAnnals of Thoracic Surgery
Volume71
Issue number1
DOIs
StatePublished - Feb 7 2001
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Coronary artery bypass grafting with cardiopulmonary bypass versus off-pump cardiopulmonary bypass grafting: Does eliminating the pump reduce morbidity and cost?'. Together they form a unique fingerprint.

  • Cite this