Correlations in umbilical blood flow Doppler velocities in the human fetus during breathing

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

We hypothesized that changes in intrathoracic pressure during fetal breathing episodes result in quantifiable variations in umbilical arterial and venous blood flow velocities, and that these variations are related to compliance properties of each system. We further hypothesized that these variations in velocities are different in fetuses with normal and abnormal umbilical arterial Doppler velocities. Umbilical arterial and venous Doppler velocities were measured simultaneously during breathing episodes in 15 normal fetuses and 14 fetuses with elevated systolic‐to‐diastolic (S/D) umbilical arterial Doppler velocity ratios. Umbilical arterial end‐diastolic velocity changes were less than umbilical venous velocity changes in normal fetuses, but were significantly greater in four fetuses with elevated S/D ratios (p < 0.004). Furthermore, umbilical arterial diastolic velocity minima preceded umbilical venous velocity minima by a time lag that was greater in fetuses with elevated S/D ratios (p < 0.002). These results suggest that differences in umbilical arterial and venous velocity variation during fetal breathing episodes may be related in part to vascular compliance, which may be altered in fetuses with abnormal umbilical arterial Doppler velocity.

Original languageEnglish (US)
Pages (from-to)361-366
Number of pages6
JournalUltrasound in Obstetrics and Gynecology
Volume4
Issue number5
DOIs
StatePublished - 1994

Keywords

  • Doppler
  • fetal breathing
  • umbilical artery

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Reproductive Medicine
  • Radiology Nuclear Medicine and imaging
  • Obstetrics and Gynecology

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