Correlations in umbilical blood flow Doppler velocities in the human fetus during breathing

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We hypothesized that changes in intrathoracic pressure during fetal breathing episodes result in quantifiable variations in umbilical arterial and venous blood flow velocities, and that these variations are related to compliance properties of each system. We further hypothesized that these variations in velocities are different in fetuses with normal and abnormal umbilical arterial Doppler velocities. Umbilical arterial and venous Doppler velocities were measured simultaneously during breathing episodes in 15 normal fetuses and 14 fetuses with elevated systolic‐to‐diastolic (S/D) umbilical arterial Doppler velocity ratios. Umbilical arterial end‐diastolic velocity changes were less than umbilical venous velocity changes in normal fetuses, but were significantly greater in four fetuses with elevated S/D ratios (p < 0.004). Furthermore, umbilical arterial diastolic velocity minima preceded umbilical venous velocity minima by a time lag that was greater in fetuses with elevated S/D ratios (p < 0.002). These results suggest that differences in umbilical arterial and venous velocity variation during fetal breathing episodes may be related in part to vascular compliance, which may be altered in fetuses with abnormal umbilical arterial Doppler velocity.

Original languageEnglish (US)
Pages (from-to)361-366
Number of pages6
JournalUltrasound in Obstetrics and Gynecology
Volume4
Issue number5
DOIs
StatePublished - 1994

Fingerprint

Umbilicus
Blood Flow Velocity
Respiration
Fetus
Compliance
Blood Vessels

Keywords

  • Doppler
  • fetal breathing
  • umbilical artery

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Reproductive Medicine
  • Radiology Nuclear Medicine and imaging
  • Obstetrics and Gynecology

Cite this

@article{592d9ceed7db411a9f756a832acb0774,
title = "Correlations in umbilical blood flow Doppler velocities in the human fetus during breathing",
abstract = "We hypothesized that changes in intrathoracic pressure during fetal breathing episodes result in quantifiable variations in umbilical arterial and venous blood flow velocities, and that these variations are related to compliance properties of each system. We further hypothesized that these variations in velocities are different in fetuses with normal and abnormal umbilical arterial Doppler velocities. Umbilical arterial and venous Doppler velocities were measured simultaneously during breathing episodes in 15 normal fetuses and 14 fetuses with elevated systolic‐to‐diastolic (S/D) umbilical arterial Doppler velocity ratios. Umbilical arterial end‐diastolic velocity changes were less than umbilical venous velocity changes in normal fetuses, but were significantly greater in four fetuses with elevated S/D ratios (p < 0.004). Furthermore, umbilical arterial diastolic velocity minima preceded umbilical venous velocity minima by a time lag that was greater in fetuses with elevated S/D ratios (p < 0.002). These results suggest that differences in umbilical arterial and venous velocity variation during fetal breathing episodes may be related in part to vascular compliance, which may be altered in fetuses with abnormal umbilical arterial Doppler velocity.",
keywords = "Doppler, fetal breathing, umbilical artery",
author = "Indik, {J. H.} and Reed, {K. L.}",
year = "1994",
doi = "10.1046/j.1469-0705.1994.04050361.x",
language = "English (US)",
volume = "4",
pages = "361--366",
journal = "Ultrasound in Obstetrics and Gynecology",
issn = "0960-7692",
publisher = "John Wiley and Sons Ltd",
number = "5",

}

TY - JOUR

T1 - Correlations in umbilical blood flow Doppler velocities in the human fetus during breathing

AU - Indik, J. H.

AU - Reed, K. L.

PY - 1994

Y1 - 1994

N2 - We hypothesized that changes in intrathoracic pressure during fetal breathing episodes result in quantifiable variations in umbilical arterial and venous blood flow velocities, and that these variations are related to compliance properties of each system. We further hypothesized that these variations in velocities are different in fetuses with normal and abnormal umbilical arterial Doppler velocities. Umbilical arterial and venous Doppler velocities were measured simultaneously during breathing episodes in 15 normal fetuses and 14 fetuses with elevated systolic‐to‐diastolic (S/D) umbilical arterial Doppler velocity ratios. Umbilical arterial end‐diastolic velocity changes were less than umbilical venous velocity changes in normal fetuses, but were significantly greater in four fetuses with elevated S/D ratios (p < 0.004). Furthermore, umbilical arterial diastolic velocity minima preceded umbilical venous velocity minima by a time lag that was greater in fetuses with elevated S/D ratios (p < 0.002). These results suggest that differences in umbilical arterial and venous velocity variation during fetal breathing episodes may be related in part to vascular compliance, which may be altered in fetuses with abnormal umbilical arterial Doppler velocity.

AB - We hypothesized that changes in intrathoracic pressure during fetal breathing episodes result in quantifiable variations in umbilical arterial and venous blood flow velocities, and that these variations are related to compliance properties of each system. We further hypothesized that these variations in velocities are different in fetuses with normal and abnormal umbilical arterial Doppler velocities. Umbilical arterial and venous Doppler velocities were measured simultaneously during breathing episodes in 15 normal fetuses and 14 fetuses with elevated systolic‐to‐diastolic (S/D) umbilical arterial Doppler velocity ratios. Umbilical arterial end‐diastolic velocity changes were less than umbilical venous velocity changes in normal fetuses, but were significantly greater in four fetuses with elevated S/D ratios (p < 0.004). Furthermore, umbilical arterial diastolic velocity minima preceded umbilical venous velocity minima by a time lag that was greater in fetuses with elevated S/D ratios (p < 0.002). These results suggest that differences in umbilical arterial and venous velocity variation during fetal breathing episodes may be related in part to vascular compliance, which may be altered in fetuses with abnormal umbilical arterial Doppler velocity.

KW - Doppler

KW - fetal breathing

KW - umbilical artery

UR - http://www.scopus.com/inward/record.url?scp=84989045961&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84989045961&partnerID=8YFLogxK

U2 - 10.1046/j.1469-0705.1994.04050361.x

DO - 10.1046/j.1469-0705.1994.04050361.x

M3 - Article

AN - SCOPUS:84989045961

VL - 4

SP - 361

EP - 366

JO - Ultrasound in Obstetrics and Gynecology

JF - Ultrasound in Obstetrics and Gynecology

SN - 0960-7692

IS - 5

ER -