Correspondence on Lovell et al. Identification of chicken genes previously assumed to be evolutionarily lost

Susanne Bornelöv, Eyal Seroussi, Sara Yosefi, Ken Pendavis, Shane C. Burgess, Manfred Grabherr, Miriam Friedman-Einat, Leif Andersson

Research output: Contribution to journalLetter

23 Scopus citations

Abstract

Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.

Original languageEnglish (US)
Article number112
JournalGenome biology
Volume18
Issue number1
DOIs
StatePublished - Jun 14 2017

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology

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    Bornelöv, S., Seroussi, E., Yosefi, S., Pendavis, K., Burgess, S. C., Grabherr, M., Friedman-Einat, M., & Andersson, L. (2017). Correspondence on Lovell et al. Identification of chicken genes previously assumed to be evolutionarily lost. Genome biology, 18(1), [112]. https://doi.org/10.1186/s13059-017-1231-1