Cost-effectiveness analysis of interferon α-2b with ribavirin for chronic hepatitis C infection

Research output: Contribution to journalReview article

3 Scopus citations


Hepatitis C infection is often referred to as the 'silent epidemic' because so many persons are unaware they are infected with the virus. Interferon α (IFN) has been the mainstay treatment for hepatitis C, but IFN monotherapy generally does not result in sustained normalization of serum alanine aminotransferase. Recently, combination therapy with IFN plus ribavirin has been shown to increase therapeutic response, but at a substantial increase in drug acquisition costs. This article provides a critique of a recently published economic analysis comparing IFN and ribavirin combination therapy with IFN monotherapy.

Original languageEnglish (US)
Pages (from-to)681-689
Number of pages9
Issue number8
StatePublished - Aug 1 2000


ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this