Cross-Resistance and Stability of Resistance to Bacillus thuringiensis Toxin Cry1C in Diamondback Moth

Yong Biao Liu, Bruce E Tabashnik, Susan K. Meyer, Neil Crickmore

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

We tested toxins of Bacillus thuringiensis against larvae from susceptible, Cry1C-resistant, and Cry1A-resistant strains of diamondback moth (Plutella xylostella). The Cry1C-resistant strain, which was derived from a field population that had evolved resistance to B. thuringiensis subsp. kurstaki and B. thuringiensis subsp. aizawai, was selected repeatedly with Cry1C in the laboratory. The Cry1C-resistant strain had strong cross-resistance to Cry1Ab, Cry1Ac, and Cry1F, low to moderate cross-resistance to Cry1Aa and Cry9Ca, and no cross-resistance to Cry1Bb, Cry1Ja, and Cry2A. Resistance to Cry1C declined when selection was relaxed. Together with previously reported data, the new data on the cross-resistance of a Cry1C-resistant strain reported here suggest that resistance to Cry1A and Cry1C toxins confers little or no cross-resistance to Cry1Bb, Cry2Aa, or Cry9Ca. Therefore, these toxins might be useful in rotations or combinations with Cry1A and Cry1C toxins. Cry9Ca was much more potent than Cry1Bb or Cry2Aa and thus might be especially useful against diamondback moth.

Original languageEnglish (US)
Pages (from-to)3216-3219
Number of pages4
JournalApplied and Environmental Microbiology
Volume67
Issue number7
DOIs
StatePublished - Jul 2001

Fingerprint

Bacillus thuringiensis
Moths
cross resistance
Plutella xylostella
moth
toxin
toxins
Bacillus thuringiensis subsp. aizawai
Larva
Bacillus thuringiensis subsp. kurstaki
larva
Population
larvae

ASJC Scopus subject areas

  • Biotechnology
  • Environmental Science(all)
  • Microbiology

Cite this

Cross-Resistance and Stability of Resistance to Bacillus thuringiensis Toxin Cry1C in Diamondback Moth. / Liu, Yong Biao; Tabashnik, Bruce E; Meyer, Susan K.; Crickmore, Neil.

In: Applied and Environmental Microbiology, Vol. 67, No. 7, 07.2001, p. 3216-3219.

Research output: Contribution to journalArticle

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