Cryptosporidium infections in mexican children: Clinical, nutritional, enteropathogenic, and diagnostic evaluations

F. Javier Enriquez, Carlos R. Avila, Jose Ignacio Santos, Jorge Tanaka-Kido, Octavio Vallejo, Charles R Sterling

Research output: Contribution to journalArticle

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Abstract

Using an indirect immunofluorescence assay on stool samples, we found a 6.4% prevalence of cryptosporidiosis among 403 children less than five years of age with acute diarrhea in Mexico City over a one-year period. The prevalence was highest (11.4%) during the rainy summer months. Most Cryptosporidium parvum cases occurred in infants less than one year of age. Cryptosporidium parvum was more common in malnourished children (P < 0.05) and in nonbreast-fed infants less than six months of age (P < 0.01). Neither dwelling characteristics nor the presence of domestic animals at home were associated with C. parvum infection. Enteropathogenic bacteria were found in 26.8% of the children; Escherichia coli, Salmonella, and Shigella being the most frequently identified. None of 100 serum samples tested showed antibodies against human immunodeficiency virus. When compared with immunofluorescence, the acid-fast technique showed a sensitivity of 76.9% and a specificity of 98.9%, with a predictive positive value of 83.3%. It was concluded that 1) monoclonal antibody-based immunofluorescence is a better diagnostic tool than the acid-fast technique, 2) the prevalence of cryptosporidiosis in this population was similar to that of other developing countries, 3) clinical manifestations were nonspecific, and 4) C. parvum was more common in malnourished children and in nonbreast-fed infants.

Original languageEnglish (US)
Pages (from-to)254-257
Number of pages4
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume56
Issue number3
StatePublished - Mar 1997

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Cryptosporidium parvum
Cryptosporidium
Cryptosporidiosis
Infection
Fluorescent Antibody Technique
Acids
Shigella
Domestic Animals
Indirect Fluorescent Antibody Technique
Mexico
Salmonella
Developing Countries
Diarrhea
Monoclonal Antibodies
HIV
Escherichia coli
Bacteria
Antibodies
Serum
Population

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Cryptosporidium infections in mexican children : Clinical, nutritional, enteropathogenic, and diagnostic evaluations. / Enriquez, F. Javier; Avila, Carlos R.; Santos, Jose Ignacio; Tanaka-Kido, Jorge; Vallejo, Octavio; Sterling, Charles R.

In: American Journal of Tropical Medicine and Hygiene, Vol. 56, No. 3, 03.1997, p. 254-257.

Research output: Contribution to journalArticle

Enriquez, F. Javier ; Avila, Carlos R. ; Santos, Jose Ignacio ; Tanaka-Kido, Jorge ; Vallejo, Octavio ; Sterling, Charles R. / Cryptosporidium infections in mexican children : Clinical, nutritional, enteropathogenic, and diagnostic evaluations. In: American Journal of Tropical Medicine and Hygiene. 1997 ; Vol. 56, No. 3. pp. 254-257.
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