Current patterns of prescribing and administering morphine in trauma patients

J. K. Whipple, K. S. Lewis, E. J. Quebbeman, M. J. Esser, M. S. Gottlieb, D. S. McKindley, M. Hess, B. A. Boucher, J. T. Jancik, L. C. Wesley, Brian L Erstad, R. K. Ausman

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Abstract

We attempted to characterize the current prescribing practices and administration patterns for intravenous intermittent morphine in trauma patients in a multicenter, open prospective, observational study. The subjects were 141 patients admitted to the surgical intensive care units (ICU) of five United States trauma centers within 12 hours of injury who received intermittent intravenous morphine for pain relief. The study was conducted from April 15, 1992, to February 15, 1993. Data obtained during the first 32 hours of the ICU stay included morphine regimen, doses administered, and time between doses. One hundred sixty-one orders were prescribed by surgeons. The most frequently ordered dose was 2-4 mg and the most frequently ordered interval was every hour as necessary. There was no relationship between the severity of injury and the minimum close ordered. During the 492 nursing shifts studied, 1257 doses were administered. Of these, 44% were at or below the minimum amount prescribed by the surgeons. Thirty three percent of the patients received a dose at an interval of more than 3 hours. We concluded that small amounts of narcotic analgesics are given to severely injured patients, and amount ordered is not affected by the severity of injury.

Original languageEnglish (US)
Pages (from-to)210-215
Number of pages6
JournalPharmacotherapy
Volume15
Issue number2
StatePublished - 1995

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Morphine
Wounds and Injuries
Intensive Care Units
Trauma Centers
Narcotics
Critical Care
Intravenous Administration
Observational Studies
Nursing
Prospective Studies
Pain
Surgeons

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Whipple, J. K., Lewis, K. S., Quebbeman, E. J., Esser, M. J., Gottlieb, M. S., McKindley, D. S., ... Ausman, R. K. (1995). Current patterns of prescribing and administering morphine in trauma patients. Pharmacotherapy, 15(2), 210-215.

Current patterns of prescribing and administering morphine in trauma patients. / Whipple, J. K.; Lewis, K. S.; Quebbeman, E. J.; Esser, M. J.; Gottlieb, M. S.; McKindley, D. S.; Hess, M.; Boucher, B. A.; Jancik, J. T.; Wesley, L. C.; Erstad, Brian L; Ausman, R. K.

In: Pharmacotherapy, Vol. 15, No. 2, 1995, p. 210-215.

Research output: Contribution to journalArticle

Whipple, JK, Lewis, KS, Quebbeman, EJ, Esser, MJ, Gottlieb, MS, McKindley, DS, Hess, M, Boucher, BA, Jancik, JT, Wesley, LC, Erstad, BL & Ausman, RK 1995, 'Current patterns of prescribing and administering morphine in trauma patients', Pharmacotherapy, vol. 15, no. 2, pp. 210-215.
Whipple JK, Lewis KS, Quebbeman EJ, Esser MJ, Gottlieb MS, McKindley DS et al. Current patterns of prescribing and administering morphine in trauma patients. Pharmacotherapy. 1995;15(2):210-215.
Whipple, J. K. ; Lewis, K. S. ; Quebbeman, E. J. ; Esser, M. J. ; Gottlieb, M. S. ; McKindley, D. S. ; Hess, M. ; Boucher, B. A. ; Jancik, J. T. ; Wesley, L. C. ; Erstad, Brian L ; Ausman, R. K. / Current patterns of prescribing and administering morphine in trauma patients. In: Pharmacotherapy. 1995 ; Vol. 15, No. 2. pp. 210-215.
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