The isolation and identification of deoxypodophyllotoxin and a new lignan, 5′‐desmethoxydeoxypodophyllotoxin, from the dried exudate of Bursera morelensis (Burseraceae) are reported. Deoxypodophyllotoxin showed high activity in the KB and PS test systems; the new lignan, although highly active against the KB test system, demonstrated only marginal activity against the PS test system. A structure is suggested for the new lignan, which was named morelensin.
- Bursera morelensis—deoxypodophyllotoxin and 5′‐des‐methoxy derivative isolated from dried exudate, cytotoxic activity evaluated
- Cytotoxic activity—deoxypodophyllotoxin and 5′‐des‐methoxy derivative evaluated
- Deoxypodophyllotoxin—and 5′‐desmethoxy derivative, isolated from dried exudate of Bursera morelensis, cytotoxic activity evaluated
ASJC Scopus subject areas
- Pharmaceutical Science