Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells

Research output: Contribution to journalComment/debate

3 Scopus citations

Abstract

Although primarily defined by their cardinal antigen-presenting function, dendritic cells (DCs) are also equipped with cytotoxic properties. We have recently reported that DCs activated by IFNc-secreting Th-1 lymphocytes can kill cancer cells and subsequently present the acquired tumor-derived antigens to T lymphocytes both in vitro and in vivo.

Original languageEnglish (US)
Pages (from-to)566-568
Number of pages3
JournalOncoImmunology
Volume1
Issue number4
DOIs
StatePublished - 2012

Keywords

  • Antigen presentation
  • Cytotoxic dendritic cells
  • Th-1 lymphocytes
  • Tumor
  • iNOS

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Oncology

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