Dad's not having much pain: Fatal forty DDI: Methadone, ciprofloxacin, CYP3A4

Rani Chovatiya, Mehmet S. Ozcan, Randal O. Dull

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This case discusses a pharmacokinetic interaction between methadone and ciprofloxacin resulting in increased sedative and analgesic effects of methadone. Methadone is a cytochrome P450 3A4 substrate and ciprofloxacin is a 3A4 inhibitor.

Original languageEnglish (US)
Title of host publicationA Case Approach to Perioperative Drug-Drug Interactions
PublisherSpringer New York
Pages249-251
Number of pages3
ISBN (Electronic)9781461474951
ISBN (Print)9781461474944
DOIs
StatePublished - Sep 15 2015
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Chovatiya, R., Ozcan, M. S., & Dull, R. O. (2015). Dad's not having much pain: Fatal forty DDI: Methadone, ciprofloxacin, CYP3A4. In A Case Approach to Perioperative Drug-Drug Interactions (pp. 249-251). Springer New York. https://doi.org/10.1007/978-1-4614-7495-1_51