De-novo biosynthesis of chlorinated aromatics by the white-rot fungus Bjerkandera sp. BOS55 Formation of 3-chloro-anisaldehyde from glucose

Ed de Jong, James A Field, Jacobus A F M Dings, Joannes B P A Wijnberg, Jan A M de Bont

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

The white-rot fungus Bjerkandera sp. BOS55 produced de-novo several aromatic metabolites. Besides veratryl alcohol and veratraldehyde, compounds which are known to be involved in the ligninolytic system of several other white-rot fungi, other metabolites were formed. These included anisaldehyde, 3-chloro-anisaldehyde and a yet unknown compound containing two chlorine atoms. Additionally GC/MS analysis revealed the production of small amounts of anisyl alcohol and 3-chloro-anisyl alcohol. After 14 days, the extracellular fluid of Bjerkandera BOS55 contained 100 μM veratraldehyde and 50 μM 3-chloro-anisaldehyde. This is the first report of de-novo biosynthesis of simple chlorinated aromatic compounds by a white-rot fungus. Anisaldehyde and 3-chloro-anisaldehyde were also produced by Bjerkandera adusta but not by Phanerochaete chrysosporium.

Original languageEnglish (US)
Pages (from-to)220-224
Number of pages5
JournalFEBS Letters
Volume305
Issue number3
DOIs
StatePublished - Jul 6 1992
Externally publishedYes

Fingerprint

Coriolaceae
Biosynthesis
Fungi
Metabolites
Glucose
Phanerochaete
Aromatic compounds
Chlorine
Extracellular Fluid
Atoms
Fluids
3-chloroanisaldehyde
veratraldehyde
anisyl alcohol
4-anisaldehyde

Keywords

  • Anisaldehyde, 3-Chloro-anisaldehyde
  • Bjerkandera
  • Lignin degradation
  • Phanerochaete chrysosporium
  • Veratryl alcohol

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

De-novo biosynthesis of chlorinated aromatics by the white-rot fungus Bjerkandera sp. BOS55 Formation of 3-chloro-anisaldehyde from glucose. / de Jong, Ed; Field, James A; Dings, Jacobus A F M; Wijnberg, Joannes B P A; de Bont, Jan A M.

In: FEBS Letters, Vol. 305, No. 3, 06.07.1992, p. 220-224.

Research output: Contribution to journalArticle

de Jong, Ed ; Field, James A ; Dings, Jacobus A F M ; Wijnberg, Joannes B P A ; de Bont, Jan A M. / De-novo biosynthesis of chlorinated aromatics by the white-rot fungus Bjerkandera sp. BOS55 Formation of 3-chloro-anisaldehyde from glucose. In: FEBS Letters. 1992 ; Vol. 305, No. 3. pp. 220-224.
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